The NKG2x/CD94 (x= A, C, E) natural killer-cell receptors perform an important role in
immunosurveillance by binding to HLA-E complexes that exclusively present peptides …

Stimulatory immune receptor NKG2D binds diverse ligands to elicit differential anti‐tumor
and anti‐virus immune responses. Two conflicting degeneracy recognition models based on …

The NKG2x/CD94 family of C-type lectin-like immunoreceptors (x= A, B, C, E, and H)
mediates surveillance of MHC class Ia cell surface expression, often dysregulated during …

The activating NKG2D receptor plays a critical role in innate and adaptive immune
responses by natural killer cells and subpopulations of T cells. The human receptor …

Human and mouse NKG 2D ligands (NKG 2 DL s) are absent or only poorly expressed by
most normal cells but are upregulated by cell stress, hence, alerting the immune system in …

γδ T cells play important roles in bridging innate and adaptive immunity, but their recognition
mechanisms remain poorly understood. Human γδ T cells of the Vδ1 subset predominate in …

The activating immunoreceptor NKG2D endows cytotoxic lymphocytes with the capacity to
recognize and eliminate infected or malignant cells. The recognition of such harmful cells is …

NKG2D is one of the most intensively studied immune receptors of the past decade. Its
unique binding and signaling properties, expression pattern, and functions have been …

We characterized two novel members of the RAET1/ULBP gene cluster, RAET1E and
RAET1G. The encoded proteins were similar to the ULBP in their class I-like α1 and α2 …

We explored the possibility to target Ewing's sarcoma family of tumors (ESFT) by redirecting
T cells. To this aim, we considered NKG2D-ligands (NKG2D-Ls) as possible target antigens …