Human cytomegalovirus-encoded UL16 discriminates MIC molecules by their α2 domains
J Spreu, T Stehle, A Steinle - The Journal of Immunology, 2006 - journals.aai.org
Human CMV infection results in MHC class I down-regulation and induction of NKG2D
ligand expression favoring NK recognition of infected cells. However, human CMV-encoded …
ligand expression favoring NK recognition of infected cells. However, human CMV-encoded …
NKG2D and related immunoreceptors
RK Strong, BJ McFarland - Advances in protein chemistry, 2004 - Elsevier
NK cells are crucial components of the innate immune system, capable of directly
eliminating infected or tumorigenic cells and regulating down-stream adaptive immune …
eliminating infected or tumorigenic cells and regulating down-stream adaptive immune …
Computational de novo peptide and protein design: rigid templates versus flexible templates
HK Fung, WJ Welsh, CA Floudas - Industrial & engineering …, 2008 - ACS Publications
Both rigid and flexible backbone design templates have been used in the numerous
computational de novo peptide and protein design efforts reported so far. In this review …
computational de novo peptide and protein design efforts reported so far. In this review …
Compositions and methods for targeted cytokine delivery
AS Krupnick, DH Fremont, ER Lazear - US Patent 11,053,293, 2021 - Google Patents
2019-04-23 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
Mouse Clr-g, a ligand for NK cell activation receptor NKR-P1F: crystal structure and biophysical properties
T Skálová, K Kotýnková, J Dušková… - The Journal of …, 2012 - journals.aai.org
Interactions between C-type lectin-like NK cell receptors and their protein ligands form one
of the key recognition mechanisms of the innate immune system that is involved in the …
of the key recognition mechanisms of the innate immune system that is involved in the …
Antibodies against human NKG2D and uses thereof
B Ursø, PANR Wagtmann, IL Pedersen - US Patent 7,879,985, 2011 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
40336450&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
40336450&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Compositions and methods for targeted cytokine delivery
AS Krupnick, ER Lazear, DH Fremont - US Patent 10,793,613, 2020 - Google Patents
2019-01-29 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
PB Rupert, M Buerger, EJ Girard, M Frutoso, D Parrilla… - Heliyon, 2024 - cell.com
NKG2D and its ligands are critical regulators of protective immune responses controlling
infections and cancer, defining a crucial immune signaling axis. Current therapeutic efforts …
infections and cancer, defining a crucial immune signaling axis. Current therapeutic efforts …
Secondary Sites of the C‐type Lectin‐Like Fold
C‐type lectins are a large superfamily of proteins involved in a multitude of biological
processes. In particular, their involvement in immunity and homeostasis has rendered them …
processes. In particular, their involvement in immunity and homeostasis has rendered them …
Homo-oligomerization of the activating natural killer cell receptor NKp30 ectodomain increases its binding affinity for cellular ligands
J Herrmann, H Berberich, J Hartmann, S Beyer… - Journal of Biological …, 2014 - ASBMB
The natural cytotoxicity receptors, comprised of three type I membrane proteins NKp30,
NKp44, and NKp46, are a unique set of activating proteins expressed mainly on the surface …
NKp44, and NKp46, are a unique set of activating proteins expressed mainly on the surface …