The human obesity gene map: the 2005 update

T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel… - …, 2006 - Wiley Online Library
This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

NPY and Y receptors: lessons from transgenic and knockout models

S Lin, D Boey, H Herzog - Neuropeptides, 2004 - Elsevier
Neuropeptide Y (NPY) in the central nervous system is a major regulator of food
consumption and energy homeostasis. It also regulates blood pressure, induces anxiolysis …

The human obesity gene map: the 2004 update

L Pérusse, T Rankinen, A Zuberi, YC Chagnon… - Obesity …, 2005 - Wiley Online Library
This paper presents the eleventh update of the human obesity gene map, which
incorporates published results up to the end of October 2004. Evidence from single‐gene …

The role of neuropeptide Y and peptide YY in the development of obesity via gut-brain axis

Y Wu, H He, Z Cheng, Y Bai… - Current Protein and …, 2019 - ingentaconnect.com
Obesity is one of the main challenges of public health in the 21st century. Obesity can
induce a series of chronic metabolic diseases, such as diabetes, dyslipidemia, hypertension …

Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action

A Laque, Y Zhang, S Gettys… - American Journal …, 2013 - journals.physiology.org
Leptin acts centrally via leptin receptor (LepRb)-expressing neurons to regulate food intake,
energy expenditure, and other physiological functions. LepRb neurons are found throughout …

Galanin and its receptors: a novel strategy for appetite control and obesity therapy

P Fang, M Yu, L Guo, P Bo, Z Zhang, M Shi - Peptides, 2012 - Elsevier
The rapid increase in the prevalence of overweight and obesity is becoming an important
health problem. Overweight and obesity may cause several metabolic complications …

Glucocorticoids decrease body weight and food intake and inhibit appetite regulatory peptide expression in the hypothalamus of rats

XY Liu, JH Shi, WH Du, YP Fan… - Experimental and …, 2011 - spandidos-publications.com
The aim of the present study was to investigate the effects of glucocorticoids (GCs) on
appetite and gene expression of the hypothalamic appetite regulatory peptides …

Galanin antagonist increases insulin resistance by reducing glucose transporter 4 effect in adipocytes of rats

L Guo, M Shi, L Zhang, G Li, L Zhang, H Shao… - General and …, 2011 - Elsevier
Seeing that galanin increases animal body weight on the conditions of inhibiting insulin
secretion and animals with metabolic disorder of galanin easily suffer from diabetes, we …

Exercise-induced galanin release facilitated GLUT4 translocation in adipocytes of type 2 diabetic rats

Y Liang, S Sheng, P Fang, Y Ma, J Li, Q Shi… - Pharmacology …, 2012 - Elsevier
Although galanin has been shown to increase insulin sensitivity in skeletal muscle of rats,
there is no literature available about the effect of galanin on Glucose Transporter 4 (GLUT4) …

Whole transcriptome analysis of hypothalamus in mice during short-term starvation

EY Oh, BS Park, HR Yang, HG Lee, TH Tu… - International Journal of …, 2023 - mdpi.com
Molecular profiling of the hypothalamus in response to metabolic shifts is a critical cue to
better understand the principle of the central control of whole-body energy metabolism. The …