[HTML][HTML] Knee osteoarthritis: epidemiology, pathogenesis, and mesenchymal stem cells: what else is new? An update

R Giorgino, D Albano, S Fusco, GM Peretti… - International journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …

[HTML][HTML] NF-κB signaling pathways in osteoarthritic cartilage destruction

MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …

Articular cartilage regeneration by activated skeletal stem cells

MP Murphy, LS Koepke, MT Lopez, X Tong… - Nature medicine, 2020 - nature.com
Osteoarthritis (OA) is a degenerative disease resulting in irreversible, progressive
destruction of articular cartilage. The etiology of OA is complex and involves a variety of …

[HTML][HTML] A plant-derived natural photosynthetic system for improving cell anabolism

P Chen, X Liu, C Gu, P Zhong, N Song, M Li, Z Dai… - Nature, 2022 - nature.com
Insufficient intracellular anabolism is a crucial factor involved in many pathological
processes in the body,. The anabolism of intracellular substances requires the consumption …

Ice-inspired lubricated drug delivery particles from microfluidic electrospray for osteoarthritis treatment

L Yang, L Sun, H Zhang, F Bian, Y Zhao - ACS nano, 2021 - ACS Publications
Particle-based drug delivery systems have a demonstrated value in osteoarthritis treatment.
Research in this area trends to developing functional particles to improve the therapeutic …

Anti‐friction MSCs delivery system improves the therapy for severe osteoarthritis

X Yan, B Yang, Y Chen, Y Song, J Ye, Y Pan… - Advanced …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a musculoskeletal disorder disease affecting about 500 million people
worldwide and mesenchymal sem cells (MSCs) therapy has been demonstrated as a …

Membranes for guided bone regeneration: a road from bench to bedside

P Aprile, D Letourneur… - Advanced healthcare …, 2020 - Wiley Online Library
Bone resorption can negatively influence the osseointegration of dental implants. Barrier
membranes for guided bone regeneration (GBR) are used to exclude nonosteogenic tissues …

Therapeutic glucocorticoids: mechanisms of actions in rheumatic diseases

RS Hardy, K Raza, MS Cooper - Nature Reviews Rheumatology, 2020 - nature.com
Therapeutic glucocorticoids have been widely used in rheumatic diseases since they
became available over 60 years ago. Despite the advent of more specific biologic therapies …

[HTML][HTML] Targeted and responsive biomaterials in osteoarthritis

J Li, H Zhang, Y Han, Y Hu, Z Geng, J Su - Theranostics, 2023 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis

TV Pereira, P Jüni, P Saadat, D Xing, L Yao, P Bobos… - bmj, 2022 - bmj.com
Objective To evaluate the effectiveness and safety of viscosupplementation for pain and
function in patients with knee osteoarthritis. Design Systematic review and meta-analysis of …