Anticancer potential of the plant‐derived Saponin Gracillin: a comprehensive review of mechanistic approaches
MS Bhuia, R Chowdhury, FA Sonia… - Chemistry & …, 2023 - Wiley Online Library
With the increasing prevalence of cancer and the toxic side effects of synthetic drugs, natural
products are being developed as promising therapeutic approaches. Gracillin is a naturally …
products are being developed as promising therapeutic approaches. Gracillin is a naturally …
Hydrogel systems for targeted cancer therapy
X Li, X Xu, M Xu, Z Geng, P Ji, Y Liu - Frontiers in Bioengineering and …, 2023 - frontiersin.org
When hydrogel materials with excellent biocompatibility and biodegradability are used as
excellent new drug carriers in the treatment of cancer, they confer the following three …
excellent new drug carriers in the treatment of cancer, they confer the following three …
TTD: Therapeutic Target Database describing target druggability information
Y Zhou, Y Zhang, D Zhao, X Yu, X Shen… - Nucleic acids …, 2024 - academic.oup.com
Target discovery is one of the essential steps in modern drug development, and the
identification of promising targets is fundamental for developing first-in-class drug. A variety …
identification of promising targets is fundamental for developing first-in-class drug. A variety …
[HTML][HTML] Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma
Y Zhu, X Jian, S Chen, G An, D Jiang, Q Yang, J Zhang… - Cell Metabolism, 2024 - cell.com
The gut microbiome has been found to play a crucial role in the treatment of multiple
myeloma (MM), which is still considered incurable due to drug resistance. In previous …
myeloma (MM), which is still considered incurable due to drug resistance. In previous …
Role of gut microbiome in cancer immunotherapy: from predictive biomarker to therapeutic target
M Zhang, J Liu, Q Xia - Experimental Hematology & Oncology, 2023 - Springer
Immunotherapy has emerged as an effective treatment for various types of cancers. Recent
studies have highlighted a significant correlation between the gut microbiome and patients' …
studies have highlighted a significant correlation between the gut microbiome and patients' …
Nano-enabled colorectal cancer therapy
Q Pan, X Fan, L Xie, D Wu, R Liu, W Gao, K Luo… - Journal of Controlled …, 2023 - Elsevier
Colorectal cancer (CRC), one of the most common and deadliest diseases worldwide, poses
a great health threat and social burden. The clinical treatments of CRC encompassing …
a great health threat and social burden. The clinical treatments of CRC encompassing …
The evolving landscape of fecal microbial transplantation
T Shao, R Hsu, C Hacein-Bey, W Zhang, L Gao… - Clinical Reviews in …, 2023 - Springer
The human gastrointestinal tract houses an enormous microbial ecosystem. Recent studies
have shown that the gut microbiota plays significant physiological roles and maintains …
have shown that the gut microbiota plays significant physiological roles and maintains …
A rodent model of human-dose-equivalent 5-fluorouracil: toxicity in the liver, kidneys, and lungs
MC da Silva, LC Fabiano, KC da Costa Salomão… - Antioxidants, 2023 - mdpi.com
5-Fluorouracil (5-FU) is a chemotherapy drug widely used to treat a range of cancer types,
despite the recurrence of adverse reactions. Therefore, information on its side effects when …
despite the recurrence of adverse reactions. Therefore, information on its side effects when …
Modulating the gut microbiota by probiotics, prebiotics, postbiotics, and fecal microbiota transplantation: An emerging trend in cancer patient care
S Ciernikova, A Sevcikova, L Drgona… - Biochimica et Biophysica …, 2023 - Elsevier
Abstract Treatment resistance, together with acute and late adverse effects, represents
critical issues in the management of cancer patients. Promising results from preclinical and …
critical issues in the management of cancer patients. Promising results from preclinical and …
Diversification and deleterious role of microbiome in gastric cancer
Gut microbiota dictates the fate of several diseases, including cancer. Most gastric cancers
(GC) belong to gastric adenocarcinomas (GAC). Helicobacter pylori colonizes the gastric …
(GC) belong to gastric adenocarcinomas (GAC). Helicobacter pylori colonizes the gastric …