Background: The BRAF V600E mutation, the most frequent genetic alteration in papillary
thyroid carcinoma (PTC), was demonstrated to be a poor prognostic factor. The aim of this …

The thyroid nodule is a common entity. Although autopsy data indicate a 50% prevalence of
thyroid nodules larger than 1 cm in patients without clinical evidence of thyroid disease, the …

Background: The accuracy of cancer detection in thyroid nodules by fine-needle aspiration
(FNA) cytology and prognostication of thyroid cancer needs further improvement and can …

Context: Because very few studies have examined the correlation between BRAF mutations
and clinicopathological features of papillary thyroid carcinoma (PTC), we analyzed here a …

The activating mutation BRAFV600E is a frequent genetic event in papillary thyroid
carcinomas (PTC) that predicts a poor prognosis, leading to loss of sodium/iodide symporter …

Tumours can arise from thyroid follicular cells if they acquire driver mutations that
constitutively activate the MAPK signalling pathway. In addition, a limited set of additional …

Background: The presence of a telomerase reverse transcriptase (TERT) promoter mutation
has been suggested as a potential prognostic marker for thyroid cancer, and a synergistic …

Context: There are no known effective and reliable biomarkers to distinguish benign thyroid
nodules from papillary thyroid carcinomas (PTC). Previous studies have indicated that …

BACKGROUND. Numerous studies have investigated the clinical significance of BRAF
mutation in papillary thyroid carcinoma (PTC). However, there have been conflicting data on …

The knowledge on thyroid cancer biology has grown over the past decade. Thus, diagnostic
and therapeutic strategies to manage thyroid cancer are rapidly evolving. With new insights …