There is now a reasonably good understanding of the key oncogenic events involved in the
initiation and progression of thyroid cancer. Many of these are characteristic of certain tumor …

Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85–
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …

The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary
thyroid cancer (PTC) has not been documented. By showing promoter methylation‐induced …

Purpose For the past 65 years, patient age at diagnosis has been widely used as a major
mortality risk factor in the risk stratification of papillary thyroid cancer (PTC), but whether this …

The aim of this study is to search for relationships between histology, radioiodine (131 I)
uptake, fluorodeoxyglucose (FDG) uptake, and disease outcome in patients with metastatic …

Carcinomas of the thyroid comprise a heterogeneous group of neoplasms with distinctive
clinical and pathological characteristics. Over the past 15 years, the application of molecular …

Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …

BRAF-activating mutations have been reported in several types of cancer, including
melanoma (∼ 70% of cases), thyroid (30-70%), ovarian (15-30%), and colorectal cancer (5 …

Context: Genetic aberration in phosphatidylinositol 3-kinase (PI3K)/AKT pathway has been
detected in numerous and diverse human cancers. PIK3CA, which encodes for the catalytic …

The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
active iodide transport into the thyroid gland and into several extrathyroidal tissues, in …