Substantial evidence suggests that chronic hyperuricemia is an independent risk factor for
hypertension, metabolic syndrome, chronic kidney disease (CKD) and cardiovascular …

Background Observational studies of the relationship between hyperuricemia and the
incidence of hypertension are controversial. We conducted a systematic review and meta …

ABSTRACT Sodium glucose cotransporter 2 (SGLT2) inhibitors have been reported to lower
the serum uric acid (SUA) level. To elucidate the mechanism responsible for this reduction …

Objective A novel rodent model and a recent randomized trial of hyperuricemic adolescents
with hypertension suggest a pathogenetic role of uric acid in hypertension, but it remains …

This review summarizes relevant studies concerning uric acid and possible links to
hypertension, renal disease, and cardiovascular disease. Whether uric acid is an …

Hyperuricaemia is common in subjects with cardiovascular disease, but is not commonly
considered a true risk factor. Recent studies suggest that uric acid is biologically active and …

Objective and sources We reviewed the epidemiologic literature for PFOA. Data synthesis
Perfluorooctanoic acid (PFOA) does not occur naturally but is present in the serum of most …

Currently, we are experiencing an epidemic of cardiorenal disease characterized by
increasing rates of obesity, hypertension, the metabolic syndrome, type 2 diabetes, and …

The definition of hyperuricemia (HU) varies widely in different studies, which makes the
epidemiological reports somewhat inconsistent. HU remains the culprit of the pathogenesis …

Experimental evidence suggests a causal role of serum uric acid (SUA) in hypertension
development. Currently, there are few data available on the association between SUA and …