Artificial Intelligence for multiple sclerosis management using retinal images: pearl, peaks, and pitfalls

S Farabi Maleki, M Yousefi, S Afshar… - Seminars in …, 2024 - Taylor & Francis
Multiple sclerosis (MS) is a complex autoimmune disease characterized by inflammatory
processes, demyelination, neurodegeneration, and axonal damage within the central …

Optical coherence tomography (OCT) measurements and cognitive performance in multiple sclerosis: a systematic review and meta-analysis

O Mirmosayyeb, R Zivadinov, B Weinstock-Guttman… - Journal of …, 2023 - Springer
Background Several studies report mixed associations between the retinal nerve fiber layer
(RNFL) thickness with cognitive and physical disability in persons with multiple sclerosis …

Retinal thinning in progressive supranuclear palsy: differences with healthy controls and correlation with clinical variables

M Picillo, G Salerno, MF Tepedino, F Abate… - Neurological …, 2022 - Springer
Background Available evidence reports conflicting data on retinal thickness in progressive
supranuclear palsy (PSP). In studies including healthy controls, PSP showed either the …

Repeated forms, testing intervals, and SDMT performance in a large multiple sclerosis dataset

TA Fuchs, J Gillies, MG Jaworski III, GE Wilding… - Multiple Sclerosis and …, 2022 - Elsevier
Abstract Background The Symbol Digit Modalities Test (SDMT), the most reliable and
sensitive measure of cognition in people with multiple sclerosis (PwMS), is increasingly …

Visuo-cognitive phenotypes in early multiple sclerosis: a multisystem model of visual processing

H Vagias, ML Byrne, L Millist, O White… - Journal of Clinical …, 2024 - mdpi.com
Background: Cognitive impairment can emerge in the earliest stages of multiple sclerosis
(MS), with heterogeneity in cognitive deficits often hindering symptom identification and …

Measuring Treatment Response in Progressive Multiple Sclerosis—Considerations for Adapting to an Era of Multiple Treatment Options

N Krajnc, T Berger, G Bsteh - Biomolecules, 2021 - mdpi.com
Disability in multiple sclerosis accrues predominantly in the progressive forms of the
disease. While disease-modifying treatment of relapsing MS has drastically evolved over the …

Low-contrast visual acuity test is associated with central inflammation and predicts disability development in newly diagnosed multiple sclerosis patients

E Dolcetti, F Buttari, A Bruno, F Azzolini, L Gilio… - Frontiers in …, 2024 - frontiersin.org
Introduction The visual system is a prominent site of damage in MS since the earliest phases
of the disease. Altered low-contrast visual acuity (LCVA) test has been associated with …

Peering further into the mind's eye: combining visual evoked potential and optical coherence tomography measures enhances insight into the variance in cognitive …

TJ Covey, D Golan, R Sergott, J Wilken, M Zarif… - Journal of …, 2024 - Springer
Abstract Background Spectral Optical Coherence Tomography (OCT) and Visual Evoked
Potentials (VEPs) have both emerged as potentially useful biomarkers of cognitive decline in …

Retinal clues for selective neuronal loss in multiple sclerosis

V Cilingir, E Seven - Neurological Sciences, 2024 - Springer
Objective The relationship between the cell body layer and the dendritic network layer of the
retina and cognitive performance (CP) in MS patients has not been examined separately …

Cognitive function in severe progressive multiple sclerosis

D Jakimovski, R Zivadinov, Z Weinstock… - Brain …, 2024 - academic.oup.com
Cognitive impairment is common in multiple sclerosis and negatively impacts quality of life.
Cognitive status has yet to be described in people with severe progressive multiple …