[HTML][HTML] The global preclinical antibacterial pipeline
U Theuretzbacher, K Outterson, A Engel… - Nature Reviews …, 2020 - nature.com
Antibacterial resistance is a great concern and requires global action. A critical question is
whether enough new antibacterial drugs are being discovered and developed. A review of …
whether enough new antibacterial drugs are being discovered and developed. A review of …
[HTML][HTML] Understanding bacteriophage tail fiber interaction with host surface receptor: the key “blueprint” for reprogramming phage host range
Bacteriophages (phages), as natural antibacterial agents, are being rediscovered because
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …
[HTML][HTML] Engineered bacteriophage therapeutics: rationale, challenges and future
M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …
Bacteriophage-based advanced bacterial detection: Concept, mechanisms, and applications
Some bacterial species are deadly disease-causing pathogens with high morbidity and
mortality in humans worldwide. Key interfaces in the transmission of bacterial pathogens …
mortality in humans worldwide. Key interfaces in the transmission of bacterial pathogens …
[HTML][HTML] Bacteriophage-mediated control of biofilm: a promising new dawn for the future
C Chang, X Yu, W Guo, C Guo, X Guo, Q Li… - Frontiers in …, 2022 - frontiersin.org
Biofilms are complex microbial microcolonies consisting of planktonic and dormant bacteria
bound to a surface. The bacterial cells within the biofilm are embedded within the …
bound to a surface. The bacterial cells within the biofilm are embedded within the …
Isolation, characterization and application of a polyvalent phage capable of controlling Salmonella and Escherichia coli O157: H7 in different food matrices
Abstract Salmonella Enteritidis, Salmonella Typhimurium, and Escherichia coli O157: H7 are
the most important foodborne pathogens, causing serious food poisoning outbreaks …
the most important foodborne pathogens, causing serious food poisoning outbreaks …
[HTML][HTML] Predicting bacteriophage hosts based on sequences of annotated receptor-binding proteins
Nowadays, bacteriophages are increasingly considered as an alternative treatment for a
variety of bacterial infections in cases where classical antibiotics have become ineffective …
variety of bacterial infections in cases where classical antibiotics have become ineffective …
[HTML][HTML] Combined use of bacteriocins and bacteriophages as food biopreservatives. A review
C Rendueles, AC Duarte, S Escobedo… - International Journal of …, 2022 - Elsevier
Throughout history, humans have consistently developed strategies to prevent food-
associated illnesses. However, despite our multiple technological advances, food safety is …
associated illnesses. However, despite our multiple technological advances, food safety is …
[HTML][HTML] Nearly complete structure of bacteriophage DT57C reveals architecture of head-to-tail interface and lateral tail fibers
R Ayala, AV Moiseenko, TH Chen, EE Kulikov… - Nature …, 2023 - nature.com
The T5 family of viruses are tailed bacteriophages characterized by a long non-contractile
tail. The bacteriophage DT57C is closely related to the paradigmal T5 phage, though it …
tail. The bacteriophage DT57C is closely related to the paradigmal T5 phage, though it …
[HTML][HTML] Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives
Clostridioides difficile, which causes life-threatening diarrheal disease, is considered an
urgent threat to healthcare setting worldwide. The current standards of care solely rely on …
urgent threat to healthcare setting worldwide. The current standards of care solely rely on …