Mesenchymal stromal/stem cells and their exosomes for restoration of spermatogenesis in non-obstructive azoospermia: a systemic review

R Zhankina, N Baghban, M Askarov… - Stem Cell Research & …, 2021 - Springer
Stem cells have been introduced as new promising therapeutic agents in treatment of
degenerative diseases because of having high differentiation potential while maintaining the …

Mesenchymal stem cells (MSCs) therapy for recovery of fertility: a systematic review

Z Fazeli, A Abedindo, MD Omrani… - Stem cell reviews and …, 2018 - Springer
In recent years, the mesenchymal stem cells (MSCs) have provided the new opportunities to
treat different disorders including infertility. Different studies have suggested that the MSCs …

[HTML][HTML] Early intervention with breast milk mesenchymal stem cells attenuates the development of diabetic-induced testicular dysfunction via hypothalamic Kisspeptin …

T Khamis, AF Abdelalim, SH Abdallah… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Diabetic male infertility and sub fertility are major complications that may implicate both
central and peripheral pathways as well as mechanisms controlling reproduction. This study …

Cisplatin-induced azoospermia and testicular damage ameliorated by adipose-derived mesenchymal stem cells

HY Ismail, NA Shaker, S Hussein, A Tohamy, M Fathi… - Biological Research, 2023 - Springer
Background The testes are highly susceptible to the adverse effects of chemotherapy and
radiation at all stages of life. Exposure to these threats mainly occurs during cancer …

Human amnion mesenchymal stem cells restore spermatogenesis in mice with busulfan-induced testis toxicity by inhibiting apoptosis and oxidative stress

C Qian, Q Meng, J Lu, L Zhang, H Li… - Stem cell research & …, 2020 - Springer
Background Before starting gonadotoxic therapies, cryopreservation of mature sperm has
been proposed worldwide as a method for male fertility preservation and for enabling the …

The role of mesenchymal stem cells in chemotherapy-induced gonadotoxicity

IO Sherif, D Sabry, A Abdel-Aziz, OM Sarhan - Stem cell research & …, 2018 - Springer
Background The therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-
MSCs) against cisplatin-induced nephrotoxicity has been reported, however, its efficacy in …

Human umbilical cord-based therapeutics: stem cells and blood derivatives for female reproductive medicine

A Rodríguez-Eguren, M Gómez-Álvarez… - International Journal of …, 2022 - mdpi.com
There are several conditions that lead to female infertility, where traditional or conventional
treatments have limited efficacy. In these challenging scenarios, stem cell (SC) therapies …

A pumpless monolayer microfluidic device based on mesenchymal stem cell-conditioned medium promotes neonatal mouse in vitro spermatogenesis

S Önen, AC Atik, M Gizer, S Köse, Ö Yaman… - Stem Cell Research & …, 2023 - Springer
Background Childhood cancer treatment-induced gonadotoxicity causes permanent
infertility/sub-infertility in nearly half of males. The current clinical and experimental …

Potential use of stem cells for fertility preservation

A Gauthier‐Fisher, A Kauffman, CL Librach - Andrology, 2020 - Wiley Online Library
Background Infertility and gonadal dysfunction can result from gonadotoxic therapies,
environmental exposures, aging, or genetic conditions. In men, non‐obstructive …

Human umbilical cord mesenchymal stem cells (hUC-MSCs) alleviate paclitaxel-induced spermatogenesis defects and maintain male fertility

YS Zhang, YN Liu, Z Teng, ZL Wang, P Zhu… - Biological Research, 2023 - Springer
Chemotherapeutic drugs can cause reproductive damage by affecting sperm quality and
other aspects of male fertility. Stem cells are thought to alleviate the damage caused by …