Objectives Evaluation and optimization of antibiotic use (antibiotic stewardship) is being
increasingly promoted as a means to reduce antibiotic resistance, adverse events, treatment …

Context Both benign prostatic hyperplasia (BPH) and cataract formation are common in
older men. The α-adrenergic receptor blocker tamsulosin is frequently prescribed to treat …

Chinese translation Background: Some evidence suggests that chlorthalidone may be
superior to hydrochlorothiazide for the treatment of hypertension. Objective: To compare the …

Background Medication non-adherence frequently leads to suboptimal patient outcomes.
Primary non-adherence, which occurs when a patient does not fill an initial prescription, is …

BACKGROUND: Angiotensin-converting enzyme inhibitors and angiotensin receptor
blockers effectively reduce blood pressure in patients with renovascular disease (RVD); yet …

Objective To evaluate the association between dementia and postoperative outcomes of
older adults with hip fractures. Design Population-based, retrospective cohort study. Setting …

Study question Do men starting treatment with prostate-specific α antagonists have
increased risk of fall and fracture? Methods Administrative datasets from the province of …

Rationale & Objective To determine whether attendance at an acute kidney injury (AKI)
follow-up clinic is associated with reduced major adverse kidney events. Study Design …

Background Clinical guidelines caution against nonsteroidal anti-inflammatory drug (NSAID)
use in older adults. The study objective was to quantify the 30-day risk of acute kidney injury …

Background Previous studies have failed to show a cardioprotective benefit of beta-blockers
in patients with stable coronary artery disease (CAD). Objectives This study sought to …