Pressurized metered-dose inhalers (pMDIs) and nebulizers are routinely employed for
aerosol delivery in mechanically ventilated patients. A significant proportion of the aerosol …

The aim of this review is to perform a critical analysis of experimental studies on aerosolized
antibiotics and draw lessons for clinical use in patients with ventilator-associated …

BACKGROUND: The position of the jet or ultrasonic nebulizer in the ventilator circuit impacts
drug delivery during mechanical ventilation, but has not been extensively explored, and no …

In selected patients, noninvasive positive pressure ventilation (NIPPV) with a facemask is
now commonly employed as the first choice for providing mechanical ventilation in the …

Gram-negative pneumonia in patients who are intubated and mechanically ventilated is
associated with increased morbidity and mortality as well as higher healthcare costs …

Pressurized metered-dose inhalers (pMDIs) and nebulizers are employed routinely for
aerosol delivery to ventilator-supported patients, but the ventilator circuit and artificial airway …

Background: Few studies on performance comparison of nebulizer systems coupled with a
single-limb circuit bilevel ventilator are available. Most of these data compared the aerosol …

Nebulized antibiotic therapy directly targets airways and lung parenchyma resulting in high
local concentrations and potentially lower systemic toxicities. Experimental and clinical …

Background: Little has been reported in terms of clinical outcomes to confirm the benefits of
nebulized bronchodilators during mechanical ventilation (MV). Electrical Impedance …

Among the devices employed for aerosol generation (metered-dose inhalers, nebulizers,
and dry powder inhalers) only metered-dose inhalers and nebulizers are routinely employed …