Responding to the opioid crisis in North America and beyond: recommendations of the Stanford–Lancet Commission
Executive summary The Stanford–Lancet Commission on the North American Opioid Crisis
was formed in response to soaring opioid-related morbidity and mortality in the USA and …
was formed in response to soaring opioid-related morbidity and mortality in the USA and …
[HTML][HTML] Historical perspective: models of Parkinson's disease
SJ Chia, EK Tan, YX Chao - International journal of molecular sciences, 2020 - mdpi.com
Parkinson's disease (PD) is the most common movement disorder with motor and nonmotor
signs. The current therapeutic regimen for PD is mainly symptomatic as the etio …
signs. The current therapeutic regimen for PD is mainly symptomatic as the etio …
[HTML][HTML] Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
MR Chuapoco, NC Flytzanis, N Goeden… - Nature …, 2023 - nature.com
Crossing the blood–brain barrier in primates is a major obstacle for gene delivery to the
brain. Adeno-associated viruses (AAVs) promise robust, non-invasive gene delivery from the …
brain. Adeno-associated viruses (AAVs) promise robust, non-invasive gene delivery from the …
Impending extinction crisis of the world's primates: Why primates matter
Nonhuman primates, our closest biological relatives, play important roles in the livelihoods,
cultures, and religions of many societies and offer unique insights into human evolution …
cultures, and religions of many societies and offer unique insights into human evolution …
Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome
E Stener-Victorin, V Padmanabhan… - Endocrine …, 2020 - academic.oup.com
More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
Evolution of prefrontal cortex
TM Preuss, SP Wise - Neuropsychopharmacology, 2022 - nature.com
Subdivisions of the prefrontal cortex (PFC) evolved at different times. Agranular parts of the
PFC emerged in early mammals, and rodents, primates, and other modern mammals share …
PFC emerged in early mammals, and rodents, primates, and other modern mammals share …
Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques
The transplantation of pancreatic islet cells could restore glycaemic control in patients with
type 1 diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic …
type 1 diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic …
Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system
J Zhang, BA Buller, ZG Zhang, Y Zhang, M Lu… - Experimental …, 2022 - Elsevier
Injury of oligodendrocytes (OLs) induces demyelination, and patients with
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …
Nanomedicine for brain cancer
CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …
treatment approaches, with mortality rates staying practically unchanged over the past 30 …
Maternal immune activation and neuropsychiatric illness: a translational research perspective
AS Brown, U Meyer - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Epidemiologic studies, including prospective birth cohort investigations, have implicated
maternal immune activation in the etiology of neuropsychiatric disorders. Maternal infectious …
maternal immune activation in the etiology of neuropsychiatric disorders. Maternal infectious …