New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …

The purpose of this systematic review was to compare the diagnostic ability of blood markers
for colorectal cancer (CRC). A systematic review of the literature for diagnostic blood …

Background: Colorectal cancer (CRC) is common and associated with significant mortality.
Current screening methods for CRC lack patient compliance. microRNAs (miRNAs) …

Colorectal cancer is one of the most prevalent cancers with high mortality in the world.
MicroRNAs are a class of small non-coding RNAs that regulate gene expression through …

MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression
predominantly by inhibiting transcription and/or promoting degradation of target mRNAs also …

Colorectal cancer (CRC) is one of the most common cancers worldwide, being the third most
diagnosed in the world and the second deadliest. Solid biopsy provides an essential guide …

Obesity is associated with insulin resistance and low-grade inflammation. Insulin resistance
is a risk factor for cancer. A recent chapter in epigenetics is represented by microRNAs …

Emerging evidence has demonstrated the feasibility of circulating miRNAs as robust non-
invasive biomarkers for the diagnosis in colorectal cancer. The use of circulating miRNAs for …

Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that is
deregulated in obesity. PPARγ exerts diverse antineoplastic effects. Attempting to determine …