Aim: DNA methylation is the best known epigenetic mark. Cancer and other pathologies
show an altered DNA methylome. However, delivering complete DNA methylation maps is …

Background Hepatic steatosis is a common chronic liver disease that can progress into more
severe stages of NAFLD or promote the development of life-threatening secondary diseases …

Early detection has the potential to reduce cancer mortality, but an effective screening test
must demonstrate asymptomatic cancer detection years before conventional diagnosis in a …

Methylation patterns of circulating cell-free DNA (cfDNA) contain rich information about
recent cell death events in the body. Here, we present an approach for unbiased …

Cell-free DNA (cfDNA) concentrations from patients with cancer are often elevated
compared with those of healthy controls, but the sources of this extra cfDNA have never …

RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation
data, providing a user-friendly analysis workflow that yields detailed hypertext reports …

Gliomas are a heterogeneous group of brain tumors with distinct biological and clinical
properties. Despite advances in surgical techniques and clinical regimens, treatment of high …

DNA methylation is a fundamental epigenetic mark that governs gene expression and
chromatin organization, thus providing a window into cellular identity and developmental …

The transition from non–muscle‐invasive bladder cancer (NMIBC) to muscle‐invasive
bladder cancer (MIBC) is detrimental to bladder cancer (BLCA) patients. Here, we aimed to …

Recurrence of meningiomas is unpredictable by current invasive methods based on
surgically removed specimens. Identification of patients likely to recur using noninvasive …