Kashin-Beck disease (KBD) is an endemic chronic osteochondral disease, which has a high
prevalence and morbidity in the Eastern Siberia of Russia, and in the broad diagonal …

The selenium content of the body is known to control the expression levels of numerous
genes, both so-called selenoproteins and non-selenoproteins. Selenium is a trace element …

Puerarin is an important active ingredient in the root of kudzu vine due to its
pharmacological properties. The aim of the present study is to contribute to the existing …

Chondrocyte is targeted for disruption in Osteoarthritis (OA) and Kashin-Beck Disease
(KBD), and chondrocyte death in cartilage may contribute to the progression of OA and KBD …

Abstract Kashin-Beck disease (KBD), a particular type of osteoarthritis (OA), and an endemic
disease with articular cartilage damage and chondrocytes apoptosis, can affect many joints …

Kashin‑Beck disease (KBD) is a chronic and endemic osteoarthropathy. The pathogenesis
of KBD has yet to be fully elucidated, although previous studies have shown that its etiology …

Objective The occurrence and development of an endemic OA, Kashin–Beck disease (KBD),
is closely related to oxidative stress induced by free radicals. The aim of the study was to find …

Kashin–Beck disease (KBD) is a special type of endemic osteoarthritis. It has been
suggested that alterations in selenium metabolism and apoptosis play a role in KBD …

Peroxiredoxin 5 is a member of the peroxiredoxin family, which has been shown to act as an
antioxidant whose main function is to reduce reactive oxygen species in cells. Peroxiredoxin …

The molecular mechanisms underlying osteoarthritis (OA) and Kashin‑Beck disease (KBD)
remain poorly understood. Hypertrophic chondrocytes serve an important role in the …