Preexposure prophylaxis for the prevention of HIV infection: evidence report and systematic review for the US Preventive Services Task Force

R Chou, C Evans, A Hoverman, C Sun, T Dana… - Jama, 2019 - jamanetwork.com
Importance Effective prevention strategies for HIV infection are an important public health
priority. Preexposure prophylaxis (PrEP) involves use of antiretroviral therapy (ART) daily or …

[HTML][HTML] Use of a vaginal ring containing dapivirine for HIV-1 prevention in women

JM Baeten, T Palanee-Phillips, ER Brown… - … England Journal of …, 2016 - Mass Medical Soc
Background Antiretroviral medications that are used as prophylaxis can prevent acquisition
of human immunodeficiency virus type 1 (HIV-1) infection. However, in clinical trials among …

Effects of pre-exposure prophylaxis for the prevention of human immunodeficiency virus infection on sexual risk behavior in men who have sex with men: a systematic …

MW Traeger, SE Schroeder, EJ Wright… - Clinical Infectious …, 2018 - academic.oup.com
Background Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is
effective in reducing HIV risk in men who have sex with men (MSM). However, concerns …

Population-level effectiveness of rapid, targeted, high-coverage roll-out of HIV pre-exposure prophylaxis in men who have sex with men: the EPIC-NSW prospective …

AE Grulich, R Guy, J Amin, F Jin, C Selvey, J Holden… - The lancet HIV, 2018 - thelancet.com
Background HIV pre-exposure prophylaxis (PrEP) is highly effective in men who have sex
with men (MSM) at the individual level, but data on population-level impact are lacking. We …

[HTML][HTML] Artificial intelligence and the implementation challenge

J Shaw, F Rudzicz, T Jamieson, A Goldfarb - Journal of medical Internet …, 2019 - jmir.org
Background Applications of artificial intelligence (AI) in health care have garnered much
attention in recent years, but the implementation issues posed by AI have not been …

Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys …

DH Barouch, FL Tomaka, F Wegmann, DJ Stieh… - The Lancet, 2018 - thelancet.com
Background More than 1· 8 million new cases of HIV-1 infection were diagnosed worldwide
in 2016. No licensed prophylactic HIV-1 vaccine exists. A major limitation to date has been …

Advantages of the parent nucleoside GS-441524 over remdesivir for Covid-19 treatment

VC Yan, FL Muller - ACS medicinal chemistry letters, 2020 - ACS Publications
While remdesivir has garnered much hope for its moderate anti-Covid-19 effects, its parent
nucleoside, GS-441524, has been overlooked. Pharmacokinetic analysis of remdesivir …

Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: a global systematic review and meta-analysis

J Zhang, C Li, J Xu, Z Hu, SE Rutstein, JD Tucker… - The lancet HIV, 2022 - thelancet.com
Background Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its
clinical and public health benefits. This study synthesises evidence regarding …

[图书][B] Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations

World Health Organization - 2016 - apps.who.int
Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations
Consolidated Guidelines on HIV prevention, diagnosis, treatment and care for key populations …

[HTML][HTML] Tenofovir-based preexposure prophylaxis for HIV infection among African women

JM Marrazzo, G Ramjee, BA Richardson… - … England Journal of …, 2015 - Mass Medical Soc
Background Reproductive-age women need effective interventions to prevent the
acquisition of human immunodeficiency virus type 1 (HIV-1) infection. Methods We …