Glucose transporters are essential for the heart to sustain its function. Due to its nature as a
high energy-consuming organ, the heart needs to catabolize a huge quantity of metabolic …

The vascular endothelium plays a vital role during embryogenesis and aging and is a cell
monolayer that lines the blood vessels. The immune system recognizes the endothelium as …

Obesity and associated diseases, such as diabetes, have reached epidemic proportions
globally. In this era of “diabesity”, white adipose tissue (WAT) has become a target of high …

The prevalence of obesity and its associated pathologies continue to increase, which has
led to a renewed interest in our major weight‐regulating organ, the white adipose tissue. It …

The vascular endothelium is present within metabolic organs and actively regulates energy
metabolism. Here we show osteocalcin, recognized as a bone-secreted metabolic hormone …

The blood-brain barrier (BBB), blood-cerebrospinal fluid (CSF) barrier (BCSFB), and CSF-
brain barriers (CSFBB) are highly regulated barriers in the central nervous system …

Vascular aging, early vascular aging or supernormal vascular aging are concepts used for
estimating the cardiovascular risk at a certain age. From the famous line of Thomas …

Introduction Recent evidence suggests that oxidative stress and endothelial dysfunction play
critical roles in the pathophysiology of COVID-19 and Long-COVID. We hypothesized that a …

Tissue engineered grafts show great potential as regenerative implants for diseased or
injured tissues within the human body. However, these grafts suffer from poor nutrient …

The liver is the central metabolic hub for carbohydrate, lipid, and protein metabolism. It is
composed of four major types of cells, including hepatocytes, endothelial cells (ECs), Kupffer …