Congenital adrenal hyperplasia—current insights in pathophysiology, diagnostics, and management

HL Claahsen-van der Grinten, PW Speiser… - Endocrine …, 2022 - academic.oup.com
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting
cortisol biosynthesis. Reduced activity of an enzyme required for cortisol production leads to …

Sex and gender in neurodevelopmental conditions

S Bölte, J Neufeld, PB Marschik, ZJ Williams… - Nature Reviews …, 2023 - nature.com
Health-related conditions often differ qualitatively or quantitatively between individuals of
different birth-assigned sexes and gender identities, and/or with different gendered …

Reinforcing rigor and reproducibility expectations for use of sex and gender in cardiovascular research

ML Lindsey, AJ LeBlanc… - American Journal …, 2021 - journals.physiology.org
In 1993, the National Institutes of Health (NIH) enacted the Revitalization Act to establish
guidelines for inclusion of women and minorities in clinical research. In 2016, the NIH …

Physiological and molecular sex differences in human skeletal muscle in response to exercise training

S Landen, D Hiam, S Voisin, M Jacques… - The Journal of …, 2023 - Wiley Online Library
Sex differences in exercise physiology, such as substrate metabolism and skeletal muscle
fatigability, stem from inherent biological factors, including endogenous hormones and …

The integration of sex and gender considerations into biomedical research: lessons from international funding agencies

J White, C Tannenbaum, I Klinge… - The Journal of …, 2021 - academic.oup.com
To improve the outcomes of research and medicine, government-based international
research funding agencies have implemented various types of policies and mechanisms …

Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton

BK Das, L Wang, T Fujiwara, J Zhou, N Aykin-Burns… - Elife, 2022 - elifesciences.org
Increased intracellular iron spurs mitochondrial biogenesis and respiration to satisfy high-
energy demand during osteoclast differentiation and bone-resorbing activities. Transferrin …

Female Olympians' voices: Female sports categories and International Olympic Committee transgender guidelines

C Devine - International Review for the Sociology of Sport, 2022 - journals.sagepub.com
The fair inclusion of female athletes at elite and Olympic levels is secured in most sports by
way of female categories because of the extensively documented biological and …

The biological basis of sex differences in athletic performance: consensus statement for the American college of sports medicine

SK Hunter, SS Angadi, A Bhargava… - … Journal of the …, 2023 - journals.lww.com
Biological sex is a primary determinant of athletic performance because of fundamental sex
differences in anatomy and physiology dictated by sex chromosomes and sex hormones …

[HTML][HTML] Examination of sex-specific participant inclusion in exercise physiology endothelial function research: a systematic review

LA Lew, JS Williams, JC Stone, AKW Au… - Frontiers in sports and …, 2022 - frontiersin.org
Background To combat historical underrepresentation of female participants in research,
guidelines have been established to motivate equal participation by both sexes. However …

[HTML][HTML] Physical fitness plays a crucial mediator role in relationships among personal, social, and lifestyle factors with adolescents' cognitive performance in a …

V Lemes, AR Gaya, KP Sadarangani… - Frontiers in …, 2021 - frontiersin.org
Background: The beneficial relationship between physical fitness and cognitive performance
is affected and modulated by a wide diversity of factors that seem to be more sensitive …