Naphthoquinones and derivatives as potential anticancer agents: An updated review

MM Rahman, MR Islam, S Akash, S Shohag… - Chemico-Biological …, 2022 - Elsevier
One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

1, 4-Naphthoquinones: some biological properties and application

D Aminin, S Polonik - Chemical and Pharmaceutical Bulletin, 2020 - jstage.jst.go.jp
Over the past decade, a number of new 1, 4-naphthoquinones have been isolated from
natural sources and new 1, 4-naphthoquinones with diverse structural features have been …

Detrimental effect of ozone on pathogenic bacteria

K Rangel, FO Cabral, GC Lechuga, JPRS Carvalho… - Microorganisms, 2021 - mdpi.com
(1) Background: Disinfection of medical devices designed for clinical use associated or not
with the growing area of tissue engineering is an urgent need. However, traditional …

1, 4-Naphthoquinone analogues: Potent antibacterial agents and mode of action evaluation

P Ravichandiran, S Sheet, D Premnath, AR Kim… - Molecules, 2019 - mdpi.com
1, 4-Naphthoquinones have antibacterial activity and are a promising new class of
compound that can be used to treat bacterial infections. The goal was to improve effective …

Synthesis and anticancer evaluation of 1, 4‐naphthoquinone derivatives containing a phenylaminosulfanyl moiety

P Ravichandiran, SA Subramaniyan, SY Kim… - …, 2019 - Wiley Online Library
Naphthoquinones are exceptional building blocks in organic synthesis and have been used
to synthesize several well‐known pharmaceutically active agents. Herein we report the …

Synthesis and antimicrobial evaluation of 1, 4‐naphthoquinone derivatives as potential antibacterial agents

P Ravichandiran, M Masłyk, S Sheet… - …, 2019 - Wiley Online Library
Naphthoquinones are an important class of compounds present in a number of natural
products. In this study, a new series of 1, 4‐naphthoquinone derivatives were synthesized …

Semisynthetic and newly designed derivatives based on natural chemical scaffolds: moving beyond natural products to fight Trypanosoma cruzi

R da Rosa, EP Schenkel, LS Campos Bernardes - Phytochemistry reviews, 2020 - Springer
Secondary metabolites obtained from natural sources are medicinally relevant molecules.
About one-third of all FDA-approved drugs are derived from or based on natural products …

[HTML][HTML] Potential of sulfur-selenium isosteric replacement as a strategy for the development of new anti-chagasic drugs

M Rubio-Hernández, V Alcolea, S Pérez-Silanes - Acta Tropica, 2022 - Elsevier
Current treatment for Chagas disease is based on only two drugs: benznidazole and
nifurtimox. Compounds containing sulfur (S) in their structure have shown promising results …

[HTML][HTML] A review on the synthesis and application of naphthoquinone-based drugs

J Khan, A Rani, M Aslam, G Pandey, BN Pant - Results in Chemistry, 2023 - Elsevier
Naphthoquinones are secondary plant metabolites that are used to treat a variety of human
ailments in traditional medicine. In light of this, the synthesis of derivatives of …

Novel 1, 4‑naphthoquinone derivatives induce reactive oxygen species‑mediated apoptosis in liver cancer cells

Y Wang, YH Luo, XJ Piao… - Molecular …, 2019 - spandidos-publications.com
Abstract Derivatives of 1, 4‑naphthoquinone have excellent anti‑cancer effects, but their use
has been greatly limited due to their serious side effects. To develop compounds with …