Synthesis, spectroscopic, thermal analysis and in vitro cytotoxicity, anticholinesterase and antioxidant activities of new Co (II), Ni (II), Cu (II), Zn (II), and Ru (III) …

R Çakmak, B Ay, E Çınar, E Başaran, S Akkoç… - Journal of Molecular …, 2023 - Elsevier
Metal-based drugs have gained significant importance in medicine in recent years. In this
research, a series of new Co (II), Ni (II), Cu (II), Zn (II), and Ru (III) complexes of a Schiff base …

[HTML][HTML] N-Acetylcysteine may exert hepatoprotective effect by regulating Meteorin-Like levels in Adriamycin-induced liver injury

S Kaya, T Yalcın, A Tektemur, T Kuloğlu - Cell Stress and Chaperones, 2023 - Elsevier
Adriamycin (ADR) is an important chemotherapeutic drug, but it has serious side effects
such as hepatotoxicity. This study aimed to evaluate whether N-acetylcysteine (NAC) has …

N-acetylcysteine may regulate altered meteorin-like levels in testicular tissue due to aluminum exposure

T Yalçın, S Kaya, T Kuloğlu, A Yiğin - Biological Trace Element Research, 2023 - Springer
Aluminum (AL) is a heavy metal known to have toxic effects on the reproductive system. It is
known that N-acetylcysteine (NAC), which has an antioxidant effect, is a useful chelator for …

Resveratrol may dose-dependently modulate nephrin and OTULIN levels in a doxorubicin-induced nephrotoxicity model

T Yalcın, S Kaya, T Kuloğlu - Toxicology Mechanisms and Methods, 2024 - Taylor & Francis
One of the most important side effects of Doxorubicin (DOX), a chemotherapeutic agent, is
nephrotoxicity. The purpose of this study is to determine whether different doses of natural …

[HTML][HTML] In an experimental myocardial infarction model, L-arginine pre-intervention may exert cardioprotective effects by regulating OTULIN levels and mitochondrial …

S Kaya, T Yalcın - Cell Stress and Chaperones, 2023 - Elsevier
The experimental myocardial infarction (MI) model originating from isoproterenol (ISO) is
frequently preferred in research due to its similarity to MI-induced damage in humans …

[HTML][HTML] Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin

T Yalçin, T Kuloğlu, NK Tektemur… - Iranian Journal of …, 2024 - ncbi.nlm.nih.gov
Objective (s): Due to its negative side effects, mainly nephrotoxicity, adriamycin (ADR) is
used fairly infrequently. The purpose of this study is to investigate the effects of N-acetyl …

[HTML][HTML] The Effect of Thymoquinone on the TNF-α/OTULIN/NF-κB Axis Against Cisplatin-İnduced Testicular Tissue Damage

T Yalçın, S Kaya, A Yiğin, CA Ağca, D Özdemir… - Reproductive …, 2024 - Springer
One of the adverse effects of the antineoplastic drug cisplatin (CS) is damage to testicular
tissue. This study aimed to examine the potential therapeutic effect of thymoquinone (TQ), a …

Potential therapeutic effect of Thymoquinone on Cisplatin-induced hepatotoxicity in rats

S Kaya, T Yalçın - 2024 - acikerisim.selcuk.edu.tr
Öz Amaç: Antineoplastik bir ajan olan Sisplatin (CIS), hepatotoksisite gibi ciddi yan etkiler
gösterir. Timokinon (ThQ), anti-inflamatuar, anti-tümöral gibi birçok faydalı etkiye sahip güçlü …