The mRNA vaccine technology era and the future control of parasitic infections
Despite intensive long-term efforts, with very few exceptions, the development of effective
vaccines against parasitic infections has presented considerable challenges, given the …
vaccines against parasitic infections has presented considerable challenges, given the …
Soil-transmitted helminths: A critical review of the impact of co-infections and implications for control and elimination
S Lebu, W Kibone, CC Muoghalu… - PLoS neglected …, 2023 - journals.plos.org
Researchers have raised the possibility that soil-transmitted helminth (STH) infections might
modify the host's immune response against other systemic infections. STH infections can …
modify the host's immune response against other systemic infections. STH infections can …
Soil-transmitted helminth vaccines: are we getting closer?
Parasitic helminths infect over one-fourth of the human population resulting in significant
morbidity, and in some cases, death in endemic countries. Despite mass drug administration …
morbidity, and in some cases, death in endemic countries. Despite mass drug administration …
Natural-product-based solutions for tropical infectious diseases
About half of the world's population and 80% of the world's biodiversity can be found in the
tropics. Many diseases are specific to the tropics, with at least 41 diseases caused by …
tropics. Many diseases are specific to the tropics, with at least 41 diseases caused by …
[HTML][HTML] Preventive chemotherapy and anthelmintic resistance of soil-transmitted helminths–Can we learn nothing from veterinary medicine?
SH Tinkler - One health, 2020 - Elsevier
Current parasite control programs in veterinary species have moved away from mass
anthelmintic treatment approaches due to the emergence of significant anthelmintic …
anthelmintic treatment approaches due to the emergence of significant anthelmintic …
Metazoan parasite vaccines: present status and future prospects
Eukaryotic parasites and pathogens continue to cause some of the most detrimental and
difficult to treat diseases (or disease states) in both humans and animals, while also …
difficult to treat diseases (or disease states) in both humans and animals, while also …
Lessons along the critical path: developing vaccines against human helminths
Helminthic parasites are important targets for vaccine research as they infect an estimated 1
billion people worldwide. Despite significant progress in the discovery of defined antigens …
billion people worldwide. Despite significant progress in the discovery of defined antigens …
Soil-transmitted helminthic vaccines: Where are we now?
It has been tested and proven that vaccination is still the best strategy to combat infectious
diseases. However, to date, there are still no vaccines against human soil-transmitted …
diseases. However, to date, there are still no vaccines against human soil-transmitted …
In silico design of a polypeptide as a vaccine candidate against ascariasis
FMD Evangelista, AHM van Vliet, SP Lawton… - Scientific reports, 2023 - nature.com
Ascariasis is the most prevalent zoonotic helminthic disease worldwide, and is responsible
for nutritional deficiencies, particularly hindering the physical and neurological development …
for nutritional deficiencies, particularly hindering the physical and neurological development …
Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics
D Sepúlveda‐Crespo, RM Reguera… - Medicinal research …, 2020 - Wiley Online Library
Helminthiasis is one of the gravest problems worldwide. There is a growing concern on less
available anthelmintics and the emergence of resistance creating a major threat to human …
available anthelmintics and the emergence of resistance creating a major threat to human …