[HTML][HTML] Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies

MF Rai, KH Collins, A Lang, T Maerz, J Geurts… - Osteoarthritis and …, 2024 - Elsevier
Objective Osteoarthritis (OA) is a complex disease involving contributions from both local
joint tissues and systemic sources. Patient characteristics, encompassing sociodemographic …

Year in review 2023: genetics, genomics, and epigenetics

A Waheed, MF Rai - Osteoarthritis and Cartilage, 2023 - Elsevier
Objective To elucidate the scientific advances made in the last 12 months within the realm of
osteoarthritis genetics, genomics, and epigenetics. This review paper highlights major …

Evolution and advancements in genomics and epigenomics in OA research: How far we have come

YFM Ramos, SJ Rice, SA Ali, C Pastrello… - Osteoarthritis and …, 2024 - Elsevier
Objective Osteoarthritis (OA) is the most prevalent musculoskeletal disease affecting
articulating joint tissues, resulting in local and systemic changes that contribute to increased …

Elevated circulating soluble interleukin-2 receptor (sCD25) level is associated with prefrontal excitatory-inhibitory imbalance in individuals with chronic pain: A proton …

J Ma, P Subramaniam, JR Yancey… - Brain, Behavior, and …, 2024 - Elsevier
Aberrant neuronal excitability in the anterior cingulate cortex (ACC) is implicated in cognitive
and affective pain processing. Such excitability may be amplified by activated circulating …

[HTML][HTML] Methods in DNA methylation array dataset analysis: A Review

K Sahoo, V Sundararajan - Computational and Structural Biotechnology …, 2024 - Elsevier
Understanding the intricate relationships between gene expression levels and epigenetic
modifications in a genome is crucial to comprehending the pathogenic mechanisms of many …

Modeling Osteoarthritis Progression with DNA Methylation Patterns from Peripheral Blood Immune Cells

CM Dunn - 2023 - search.proquest.com
Osteoarthritis (OA) is a chronic, degenerative, musculoskeletal disease that is the leading
cause of disability in the United States. OA affects over 32 million adults in the US resulting …

Outcome-guided Bayesian Clustering for Disease Subtype Discovery Using High-dimensional Transcriptomic Data

L Meng, Z Huo - arXiv preprint arXiv:2107.05933, 2021 - arxiv.org
The discovery of disease subtypes is an essential step for developing precision medicine,
and disease subtyping via omics data has become a popular approach. While promising …

[引用][C] Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies

M Farooq Rai, KH Collins, A Lang, T Maerz, J Geurts… - 2023 - Elsevier BV