Biological implications of polydimethylsiloxane-based microfluidic cell culture

KJ Regehr, M Domenech, JT Koepsel, KC Carver… - Lab on a Chip, 2009 - pubs.rsc.org
Polydimethylsiloxane (PDMS) has become a staple of the microfluidics community by virtue
of its simple fabrication process and material attributes, such as gas permeability, optical …

[HTML][HTML] In vitro models for non-alcoholic fatty liver disease: Emerging platforms and their applications

MJ Ramos, L Bandiera, F Menolascina, JA Fallowfield - Iscience, 2022 - cell.com
Non-alcoholic fatty liver disease (NAFLD) represents a global healthcare challenge,
affecting 1 in 4 adults, and death rates are predicted to rise inexorably. The progressive form …

[HTML][HTML] One-step fabrication of an organ-on-a-chip with spatial heterogeneity using a 3D bioprinting technology

H Lee, DW Cho - Lab on a Chip, 2016 - pubs.rsc.org
Although various types of organs-on-chips have been introduced recently as tools for drug
discovery, the current studies are limited in terms of fabrication methods. The fabrication …

Cell-printed 3D liver-on-a-chip possessing a liver microenvironment and biliary system

H Lee, S Chae, JY Kim, W Han, J Kim, Y Choi… - …, 2019 - iopscience.iop.org
To overcome the drawbacks of in vitro liver testing during drug development, numerous liver-
on-a-chip models have been developed. However, current liver-on-a-chip technologies are …

[HTML][HTML] The impact of microfluidics in high-throughput drug-screening applications

P De Stefano, E Bianchi, G Dubini - Biomicrofluidics, 2022 - pubs.aip.org
Drug discovery is an expensive and lengthy process. Among the different phases, drug
discovery and preclinical trials play an important role as only 5–10 of all drugs that begin …

Engineering systems for the generation of patterned co-cultures for controlling cell–cell interactions

H Kaji, G Camci-Unal, R Langer… - Biochimica et Biophysica …, 2011 - Elsevier
BACKGROUND: Inside the body, cells lie in direct contact or in close proximity to other cell
types in a tightly controlled architecture that often regulates the resulting tissue function …

[HTML][HTML] Highly stable liquid metal-based pressure sensor integrated with a microfluidic channel

T Jung, S Yang - Sensors, 2015 - mdpi.com
Pressure measurement is considered one of the key parameters in microfluidic systems. It
has been widely used in various fields, such as in biology and biomedical fields. The …

[HTML][HTML] Development of lumen-based perfusable 3D liver in vitro model using single-step bioprinting with composite bioinks

S Maji, M Lee, J Lee, J Lee, H Lee - Materials today bio, 2023 - Elsevier
Hepatic sinusoids are uniquely organized structures that help maintain a spectrum of
hepatic functions. Although several in vitro liver models have been developed to replicate …

Integrated ionic liquid-based electrofluidic circuits for pressure sensing within polydimethylsiloxane microfluidic systems

CY Wu, WH Liao, YC Tung - Lab on a Chip, 2011 - pubs.rsc.org
This paper reports a novel pressure sensor with an electrical readout based on electrofluidic
circuits constructed by ionic liquid (IL)-filled microfluidic channels. The developed pressure …

A microfluidic device for uniform-sized cell spheroids formation, culture, harvesting and flow cytometry analysis

B Patra, YH Chen, CC Peng, SC Lin, CH Lee… - …, 2013 - pubs.aip.org
A microfluidic device for uniform-sized cell spheroids formation, culture, harvesting and flow
cytometry analysis | Biomicrofluidics | AIP Publishing Skip to Main Content Umbrella Alt Text …