The challenge by multiple environmental and biological factors induce inflammation in aging: their role in the promotion of chronic disease

MC Bachmann, S Bellalta, R Basoalto… - Frontiers in …, 2020 - frontiersin.org
The aging process is driven by multiple mechanisms that lead to changes in energy
production, oxidative stress, homeostatic dysregulation and eventually to loss of functionality …

Potential cytotoxicity of trace elements and polycyclic aromatic hydrocarbons bounded to particulate matter: a review on in vitro studies on human lung epithelial cells

M Kermani, T Rahmatinia, V Oskoei, S Norzaee… - … Science and Pollution …, 2021 - Springer
A large number of studies have been conducted for clarifying toxicological mechanisms of
particulate matter (PM) aimed to investigate the physicochemical properties of PM and …

Air pollution-derived PM2. 5 impairs mitochondrial function in healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells

B Leclercq, J Kluza, S Antherieu, J Sotty… - Environmental …, 2018 - Elsevier
In order to clarify whether the mitochondrial dysfunction is closely related to the cell
homeostasis maintenance after particulate matter (PM 2.5) exposure, oxidative …

PM2. 5 induces male reproductive toxicity via mitochondrial dysfunction, DNA damage and RIPK1 mediated apoptotic signaling pathway

J Zhang, J Liu, L Ren, J Wei, J Duan, L Zhang… - Science of The Total …, 2018 - Elsevier
Recent years, air pollution has been a serious problem, and PM 2.5 is the main air
particulate pollutant. Studies have investigated that PM 2.5 is a risky factor to the …

Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression

CV Breton, AY Song, J Xiao, SJ Kim, HH Mehta, J Wan… - Mitochondrion, 2019 - Elsevier
Mitochondrial DNA is sensitive to damage by exogenous reactive oxygen sources, including
traffic-related air pollution (TRAP). Given the important role for mitochondria in human …

Urban fine particulate matter (PM2. 5) exposure destroys blood–testis barrier (BTB) integrity through excessive ROS-mediated autophagy

Y Wei, XN Cao, XL Tang, LJ Shen, T Lin… - Toxicology …, 2018 - Taylor & Francis
Context: Blood–testis barrier (BTB), constituted by tight junctions (TJs), adherens junctions
and gap junctions, is important for spermatogenesis. PM2. 5 is known to impair testicular …

[HTML][HTML] Exposure to nonylphenol in early life causes behavioural deficits related with autism spectrum disorders in rats

M You, S Li, S Yan, D Yao, T Wang, Y Wang - Environment International, 2023 - Elsevier
Early-life exposure to environmental endocrine disruptors (EDCs) is a potential risk factor for
autism spectrum disorder (ASD). Exposure to nonylphenol (NP), a typical EDC, is known to …

Transport most likely to cause air pollution peak exposures in everyday life: Evidence from over 2000 days of personal monitoring

E Dons, M Laeremans, JP Orjuela… - Atmospheric …, 2019 - Elsevier
Background Air quality standards are typically based on long term averages–whereas a
person may encounter exposure peaks throughout the day. Exposure peaks may contribute …

Exposure to PM2. 5 aggravates Parkinson's disease via inhibition of autophagy and mitophagy pathway

Y Wang, C Li, X Zhang, X Kang, Y Li, W Zhang, Y Chen… - Toxicology, 2021 - Elsevier
Extensive health studies had declared that exposure to particulate matter (PM) was closely
associated with neurodegenerative diseases, ie Parkinson's disease (PD). Our aim was to …

Ambient particulate matter triggers dysfunction of subcellular structures and endothelial cell apoptosis through disruption of redox equilibrium and calcium …

Y Wang, T Wu, M Tang - Journal of hazardous materials, 2020 - Elsevier
Ambient particulate matter (APM) is becoming a global environmental problem that seriously
jeopardizes public health. Previous evidence hinted that APM correlates to cardiovascular …