Regulation of embryonic stem cell self-renewal
G Chen, S Yin, H Zeng, H Li, X Wan - Life, 2022 - mdpi.com
Embryonic stem cells (ESCs) are a type of cells capable of self-renewal and multi-directional
differentiation. The self-renewal of ESCs is regulated by factors including signaling pathway …
differentiation. The self-renewal of ESCs is regulated by factors including signaling pathway …
RNA interference nanotherapeutics for treatment of glioblastoma multiforme
P Singh, A Singh, S Shah, J Vataliya… - Molecular …, 2020 - ACS Publications
Nucleic acid therapeutics for RNA interference (RNAi) are gaining attention in the treatment
and management of several kinds of the so-called “undruggable” tumors via targeting …
and management of several kinds of the so-called “undruggable” tumors via targeting …
Capturing transitional pluripotency through proline metabolism
In this paper, we summarize the current knowledge of the role of proline metabolism in the
control of the identity of Embryonic Stem Cells (ESCs). An imbalance in proline metabolism …
control of the identity of Embryonic Stem Cells (ESCs). An imbalance in proline metabolism …
Single-cell profiling of coding and noncoding genes in human dopamine neuron differentiation
Dopaminergic (DA) neurons derived from human pluripotent stem cells (hPSCs) represent a
renewable and available source of cells useful for understanding development, developing …
renewable and available source of cells useful for understanding development, developing …
[HTML][HTML] Unraveling the Role of Bromodomain and Extra-Terminal Proteins in Human Uterine Leiomyosarcoma
Uterine leiomyosarcoma (uLMS) is the most common type of uterine sarcoma, associated
with poor prognosis, high rates of recurrence, and metastasis. Currently, the molecular …
with poor prognosis, high rates of recurrence, and metastasis. Currently, the molecular …
[HTML][HTML] Network characterization linc1393 in the maintenance of pluripotency provides the principles for lncRNA targets prediction
W Hou, M Zong, Q Zhao, X Yang, J Zhang, S Liu, X Li… - Iscience, 2023 - cell.com
Long non-coding RNAs (lncRNAs) have been implicated in diverse biological processes.
However, the functional mechanisms have not yet been fully explored. Characterizing the …
However, the functional mechanisms have not yet been fully explored. Characterizing the …
Regulation of CD8 T Cell Differentiation by the RNA-Binding Protein DDX5
TL Louis, WH Wong, P Yao, NS Kurd, T Tysl… - The Journal of …, 2023 - journals.aai.org
The RNA-binding protein DEAD-box protein 5 (DDX5) is a polyfunctional regulator of gene
expression, but its role in CD8+ T cell biology has not been extensively investigated. In this …
expression, but its role in CD8+ T cell biology has not been extensively investigated. In this …
The Functional Role and Regulatory Mechanism of FTO m6A RNA Demethylase in Human Uterine Leiomyosarcoma
Q Yang, A Al-Hendy - International Journal of Molecular Sciences, 2023 - mdpi.com
Uterine leiomyosarcoma (uLMS) is the most frequent subtype of uterine sarcoma that
presents a poor prognosis and high rates of recurrence and metastasis. The origin and …
presents a poor prognosis and high rates of recurrence and metastasis. The origin and …
Sex determining systems of Drosophila control somatic sexual differentiation by cytoplasmic determinants and inductive signals: an insight from pattern development …
RN Chatterjee - The Nucleus, 2024 - Springer
In Drosophila melanogaster, sexual adaptation shapes the chromosomal level genome
organization, by which an embryo with the X: A ratio 0.5 develop into a male and an embryo …
organization, by which an embryo with the X: A ratio 0.5 develop into a male and an embryo …
Interplay between DNA and RNA modifications: A constantly evolving process
The epigenome refers to the entirety of DNA methylations, histone modifications,
nucleosome occupancy, and coding and non-coding RNAs (and their modifications) in …
nucleosome occupancy, and coding and non-coding RNAs (and their modifications) in …