Preoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis
Background: The benefit of neoadjuvant chemoradiotherapy in oesophageal cancer has
been extensively studied but data on survival are still equivocal. Objective: To assess the …
been extensively studied but data on survival are still equivocal. Objective: To assess the …
[HTML][HTML] The effect of digoxin on mortality and morbidity in patients with heart failure
Digitalis Investigation Group - New England Journal of Medicine, 1997 - Mass Medical Soc
Background The role of cardiac glycosides in treating patients with chronic heart failure and
normal sinus rhythm remains controversial. We studied the effect of digoxin on mortality and …
normal sinus rhythm remains controversial. We studied the effect of digoxin on mortality and …
A consumer's guide to subgroup analyses
▪ The extent to which a clinician should believe and act on the results of subgroup analyses
of data from randomized trials or meta-analyses is controversial. Guidelines are provided in …
of data from randomized trials or meta-analyses is controversial. Guidelines are provided in …
Preoperative radiotherapy for resectable rectal cancer: a meta-analysis
ContextThe benefit of adjuvant radiotherapy for resectable rectal cancer has been
extensively studied, but data on survival are still equivocal despite a reduction in the rate of …
extensively studied, but data on survival are still equivocal despite a reduction in the rate of …
Inpatient general medicine is evidence based
DL Sackett, J Ellis, I Mulligan, J Rowe - The Lancet, 1995 - thelancet.com
For many years clinicians have had to cope with the accusation that only 10-20% of the
treatments they provide have any scientific foundation. Their interventions, in other words …
treatments they provide have any scientific foundation. Their interventions, in other words …
Rating the quality of evidence for clinical practice guidelines
DC Hadorn, D Baker, JS Hodges, N Hicks - Journal of clinical epidemiology, 1996 - Elsevier
This article describes the system for rating the quality of medical evidence developed and
used during creation of the Agency for Health Care Policy and Research-sponsored heart …
used during creation of the Agency for Health Care Policy and Research-sponsored heart …
Inotropes
GS Francis, JA Bartos, S Adatya - Journal of the American College of …, 2014 - jacc.org
Inotropes have been fundamental to resuscitation of acute cardiogenic shock for decades.
Heart failure and cardiogenic shock, in severe cases, are syndromes characterized in many …
Heart failure and cardiogenic shock, in severe cases, are syndromes characterized in many …
Prevention of first bleeding in cirrhosis: a meta-analysis of randomized trials of nonsurgical treatment
L Pagliaro, G D'Amico, TIA Sörensen… - Annals of Internal …, 1992 - acpjournals.org
▪ Objective: To assess the effectiveness of β-blockers and endoscopic sclerotherapy in the
prevention of first bleeding and reduction of mortality in patients with cirrhosis and …
prevention of first bleeding and reduction of mortality in patients with cirrhosis and …
Clinical use of digitalis: a state of the art review
TF Whayne Jr - American journal of cardiovascular drugs, 2018 - Springer
The history of digitalis is rich and interesting, with the first use usually attributed to William
Withering and his study on the foxglove published in 1785. However, some knowledge of …
Withering and his study on the foxglove published in 1785. However, some knowledge of …