[PDF][PDF] The protective roles of citrus flavonoids, naringenin, and naringin on endothelial cell dysfunction in diseases

JA Adetunji, KD Fasae, AI Awe, OK Paimo… - Heliyon, 2023 - cell.com
The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …

[HTML][HTML] The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline

J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …

Plausible antioxidant and anticonvulsant potential of brain targeted naringenin-conjugated graphene oxide nanoparticles

R Murugan, G Mukesh, B Haridevamuthu… - Biomass Conversion …, 2023 - Springer
Epilepsy is a condition in the brain cause frequent seizures and related comorbidities. The
major hindrance during the design of antiepileptic drugs is their permeability through the …

Nose to brain delivery of naringin-loaded chitosan nanoparticles for potential use in oxaliplatin-induced chemobrain in rats: impact on oxidative stress, cGAS/STING …

DMF Hanna, J Youshia, SF Fahmy… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Objectives Oxaliplatin induces chemobrain in cancer patients/survivors. Nutraceutical
naringin has antioxidant and anti-inflammatory properties with low oral bioavailability. Our …

Liraglutide and Naringenin relieve depressive symptoms in mice by enhancing Neurogenesis and reducing inflammation

YS Abdelkawy, M Elharoun, E Sheta… - European Journal of …, 2024 - Elsevier
Depression is a debilitating mental disease that negatively impacts individuals' lives and
society. Novel hypotheses have been recently proposed to improve our understanding of …

[HTML][HTML] Oligonol ameliorates liver function and brain function in the 5× FAD mouse model: transcriptional and cellular analysis

D Jo, A Arjunan, S Choi, YS Jung, J Park, J Jo… - Food & Function, 2023 - pubs.rsc.org
Alzheimer's disease (AD) is a common neurodegenerative disease worldwide and is
accompanied by memory deficits, personality changes, anxiety, depression, and social …

[HTML][HTML] Insights into the Neuroprotective Potential of Epicatechin: Effects against Aβ-Induced Toxicity in Caenorhabditis elegans

B Ayuda-Durán, L Garzón-García… - Antioxidants, 2024 - mdpi.com
Medical therapies to avoid the progression of Alzheimer's disease (AD) are limited to date.
Certain diets have been associated with a lower incidence of neurodegenerative diseases …

Naringin: A flavanone with a multifaceted target against sepsis-associated organ injuries

B Bajgai, M Suri, H Singh, M Hanifa, JS Bhatti… - Phytomedicine, 2024 - Elsevier
Background Sepsis causes multiple organ dysfunctions and raises mortality and morbidity
rates through a dysregulated host response to infection. Despite the growing research …

Phytic acid attenuates acetaminophen-induced hepatotoxicity via modulating iron-mediated oxidative stress and SIRT-1 expression in mice

HM Hassan, NHM Abdel-Halim… - Frontiers in …, 2024 - frontiersin.org
Introduction: Administration of high doses of acetaminophen (APAP) results in liver injury.
Oxidative stress and iron overload play roles in the pathogenesis of APAP-induced …

[HTML][HTML] Probiotics Attenuate Myopathic Changes in Aging Rats via Activation of the Myogenic Stellate Cells

NHM Abdel-Halim, EAE Farrag, MO Hammad… - Probiotics and …, 2023 - Springer
Aging represents a complex biological process associated with decline in skeletal muscle
functions. Aging impairs satellite cells that serve as muscle progenitor cells. Probiotic …