Role of estrogen receptors in health and disease
P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …
Abnormal ER signaling may result in various disorders, including reproductive system …
Sexual dimorphism in colon cancer
M Abancens, V Bustos, H Harvey, J McBryan… - Frontiers in …, 2020 - frontiersin.org
A higher incidence of colorectal cancer (CRC) is found in males compared to females.
Young women (18–44 years) with CRC have a better survival outcome compared to men of …
Young women (18–44 years) with CRC have a better survival outcome compared to men of …
High-fat diet and estrogen modulate the gut microbiota in a sex-dependent manner in mice
L Hases, L Stepanauskaite, M Birgersson… - Communications …, 2023 - nature.com
A high-fat diet can lead to gut microbiota dysbiosis, chronic intestinal inflammation, and
metabolic syndrome. Notably, resulting phenotypes, such as glucose and insulin levels …
metabolic syndrome. Notably, resulting phenotypes, such as glucose and insulin levels …
Genistein-derived ROS-responsive nanoparticles relieve colitis by regulating mucosal homeostasis
W Fan, S Zhang, Y Wu, T Lu, J Liu, X Cao… - … Applied Materials & …, 2021 - ACS Publications
Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
Dietary fiber intake and all-cause and cause-specific mortality: An updated systematic review and meta-analysis of prospective cohort studies
F Ramezani, F Pourghazi, M Eslami, M Gholami… - Clinical Nutrition, 2023 - Elsevier
Background Accumulating evidence supports the effects of dietary fiber on the risk of non-
communicable diseases (NCDs). However, there is no updated systematic review and meta …
communicable diseases (NCDs). However, there is no updated systematic review and meta …
Implications of estrogen and its receptors in colorectal carcinoma
Estrogens have been implicated in the pathogenesis of various cancer types, including
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …
High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner
L Hases, A Archer, R Indukuri, M Birgersson, C Savva… - Scientific reports, 2020 - nature.com
There is a strong association between obesity and colorectal cancer (CRC), especially in
men, whereas estrogen protects against both the metabolic syndrome and CRC. Colon is …
men, whereas estrogen protects against both the metabolic syndrome and CRC. Colon is …
[HTML][HTML] Sex difference of colon adenoma pathway and colorectal carcinogenesis
Y Choi, N Kim - The World Journal of Men's Health, 2024 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common causes of cancer morbidity in both
sexes but shows sex differences. First, sex-specific differences in tumor recurrence and …
sexes but shows sex differences. First, sex-specific differences in tumor recurrence and …
[HTML][HTML] Elevated MMP10/13 mediated barrier disruption and NF-κB activation aggravate colitis and colon tumorigenesis in both individual or full miR-148/152 family …
K Tang, Z Wu, M Sun, X Huang, J Sun, J Shi, X Wang… - Cancer Letters, 2022 - Elsevier
Dynamic miRNA alteration is known to occur in colitis-associated colon cancer (CAC), while
the molecular mechanisms underpinning how miRNAs modulate the development from …
the molecular mechanisms underpinning how miRNAs modulate the development from …
[HTML][HTML] p-Hydroxybenzoic acid alleviates inflammatory responses and intestinal mucosal damage in DSS-induced colitis by activating ERβ signaling
X Xu, A Luo, X Lu, M Liu, H Wang, H Song… - Journal of Functional …, 2021 - Elsevier
Abstract p-Hydroxybenzaldehyde (HD), the main active component of Nostoc commune, has
been shown to attenuate dextran sulfate sodium (DSS)-induced experimental colitis …
been shown to attenuate dextran sulfate sodium (DSS)-induced experimental colitis …