The mechanism and therapy of aortic aneurysms

J Gao, H Cao, G Hu, Y Wu, Y Xu, H Cui, HS Lu… - Signal transduction and …, 2023 - nature.com
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Effect of surface ligand modification on the properties of anti-tumor nanocarrier

N Ying, X Lin, M Xie, D Zeng - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
With the continuous increasing number of cancer patients worldwide, there has been great
interest in developing the targeted delivery anti-cancer drugs. The drug concentration …

[HTML][HTML] The novel hepatoprotective mechanisms of silibinin-phospholipid complex against d-GalN/LPS-induced acute liver injury

S Tang, X Zhang, Z Duan, M Xu, M Kong… - International …, 2023 - Elsevier
Abstract Background & Aims Silibinin-phospholipid complex (SPC) has been utilized to treat
acute liver injury clinically. Nevertheless, the hepatoprotective mechanism of SPC remains …

[HTML][HTML] Colchicine ameliorates short-term abdominal aortic aneurysms by inhibiting the expression of NLRP3 inflammasome components in mice

J Hu, J Xu, J Zhao, Y Liu, R Huang, D Yao, J Xie… - European journal of …, 2024 - Elsevier
Background Abdominal aortic aneurysms (AAA) are often associated with chronic
inflammation and pose a significant risk to affected individuals. Colchicine, known for its anti …

[HTML][HTML] The role of immune mechanisms in abdominal aortic aneurysm: could it be a promising therapeutic strategy?

R Dinc - Acta Cardiologica Sinica, 2023 - ncbi.nlm.nih.gov
Abdominal aortic aneurysm (AAA) is an enlargement of the aorta greater than 50% in
diameter. Although up to 80% of cases result in mortality if the aneurysm ruptures, patients …

MicroRNAs in T cell-immunotherapy

SG Dosil, A Rodríguez-Galán… - International Journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) act as master regulators of gene expression in homeostasis and
disease. Despite the rapidly growing body of evidence on the theranostic potential of …

Biomimetic Systems Involving Macrophages and Their Potential for Targeted Drug Delivery

IV Savchenko, ID Zlotnikov, EV Kudryashova - Biomimetics, 2023 - mdpi.com
The concept of targeted drug delivery can be described in terms of the drug systems' ability
to mimic the biological objects' property to localize to target cells or tissues. For example …