Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …

Skeletal muscle contains intramyocellular lipid droplets within the cytoplasm of myocytes as
well as intermuscular adipocytes. These depots exhibit physiological and pathological …

A growing body of scientific literature suggests that not only changes in skeletal muscle
mass, but also other factors underpinning muscle quality, play a role in the decline in …

OBJECTIVE—The purpose of this article was to determine the relationships among total
body fat, visceral adipose tissue (VAT), fat cell size (FCS), ectopic fat deposition in liver …

Objective: We examined the relationships between computed tomography (CT)–defined
skeletal muscle parameters and the systemic inflammatory response (SIR) in patients with …

Muscle quality (MQ), defined as the amount of strength and/or power per unit of muscle
mass, is a novel index of functional capacity that is increasingly relied upon as a critical …

Background & aims Profound weight loss and malnutrition subsequent to severe dysphagia
and cancer cachexia are cardinal symptoms in oesophageal cancer (OC). Low muscle …

OBJECTIVE—Reduced mitochondrial capacity in skeletal muscle occurs in type 2 diabetic
patients and in those at increased risk for this disorder, but the extent to which mitochondrial …

Calorie restriction (CR) triggers benefits for healthspan including decreased risk of
cardiometabolic disease (CVD). In an ancillary study to CALERIE 2, a 24-mo 25% CR study …

It is unclear whether regular exercise alone (no caloric restriction) is a useful strategy to
reduce adiposity and obesity-related metabolic risk factors in obese girls. We examined the …