[HTML][HTML] Advances in structure-based drug design targeting membrane protein markers in prostate cancer
JP Batista-Silva, D Gomes, SF Sousa, Â Sousa… - Drug Discovery …, 2024 - Elsevier
Prostate cancer (PCa) is one of the leading cancers in men and the lack of suitable
biomarkers or their modulators results in poor prognosis. Membrane proteins (MPs) have a …
biomarkers or their modulators results in poor prognosis. Membrane proteins (MPs) have a …
Evolution, classification, and mechanisms of transport, activity regulation, and substrate specificity of ZIP metal transporters
Abstract The Zrt/Irt-like protein (ZIP) family consists of ubiquitously expressed divalent d-
block metal transporters that play central roles in the uptake, secretion, excretion, and …
block metal transporters that play central roles in the uptake, secretion, excretion, and …
The membrane androgen receptor ZIP9 (SCL39A9) maintains ovarian homeostasis by mediating post-ovulatory follicle breakdown in zebrafish
A Converse, H Genuise, TL Bennett, RM Butler… - General and …, 2023 - Elsevier
ZIP9 was recently characterized as a membrane androgen receptor in Atlantic croaker
granulosa/theca (G/T) cells where it mediates androgen-induced apoptosis in vitro, but the …
granulosa/theca (G/T) cells where it mediates androgen-induced apoptosis in vitro, but the …
The role of ZIP9 and androgen receptor in the establishment of tight junctions between adult rat sertoli cells
H Kabbesh, A Bulldan, L Konrad, G Scheiner-Bobis - Biology, 2022 - mdpi.com
Simple Summary Haploid male germ cells that originate at the onset of puberty from diploid
precursor cells would be attacked by the innate immune system if they were not protected by …
precursor cells would be attacked by the innate immune system if they were not protected by …
[HTML][HTML] ZIP9 mediates the effects of DHT on learning, memory and hippocampal synaptic plasticity of male Tfm and APP/PS1 mice
L Song, H Chen, D Qiao, B Zhang, F Guo… - Frontiers in …, 2023 - frontiersin.org
Androgens are closely associated with functions of hippocampal learning, memory, and
synaptic plasticity. The zinc transporter ZIP9 (SLC39A9) regulates androgen effects as a …
synaptic plasticity. The zinc transporter ZIP9 (SLC39A9) regulates androgen effects as a …
Tetrapeptides modelled to the androgen binding site of ZIP9 stimulate expression of tight junction proteins and tight junction formation in sertoli cells
ML Möller, A Bulldan, G Scheiner-Bobis - Biology, 2021 - mdpi.com
Simple Summary Androgens such as testosterone act either through the nuclear androgen
receptor or through the plasma membrane-bound androgen receptor ZIP9. Androgens are …
receptor or through the plasma membrane-bound androgen receptor ZIP9. Androgens are …