The cell biology of archaea

M van Wolferen, AA Pulschen, B Baum, S Gribaldo… - Nature …, 2022 - nature.com
The past decade has revealed the diversity and ubiquity of archaea in nature, with a growing
number of studies highlighting their importance in ecology, biotechnology and even human …

Structural and functional diversity of type IV secretion systems

TRD Costa, JB Patkowski, K Macé, PJ Christie… - Nature Reviews …, 2024 - nature.com
Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …

mobileOG-db: a manually curated database of protein families mediating the life cycle of bacterial mobile genetic elements

CL Brown, J Mullet, F Hindi, JE Stoll… - Applied and …, 2022 - Am Soc Microbiol
Bacterial mobile genetic elements (MGEs) encode functional modules that perform both core
and accessory functions for the element, the latter of which are often only transiently …

[HTML][HTML] Cryo-EM structure of a type IV secretion system

K Macé, AK Vadakkepat, A Redzej, N Lukoyanova… - Nature, 2022 - nature.com
Bacterial conjugation is the fundamental process of unidirectional transfer of DNAs, often
plasmid DNAs, from a donor cell to a recipient cell. It is the primary means by which …

[HTML][HTML] Molecular architecture of bacterial type IV secretion systems

MJ Sheedlo, MD Ohi, DB Lacy, TL Cover - PLoS pathogens, 2022 - journals.plos.org
Bacterial type IV secretion systems (T4SSs) are a versatile group of nanomachines that can
horizontally transfer DNA through conjugation and deliver effector proteins into a wide range …

[HTML][HTML] Archaeal DNA-import apparatus is homologous to bacterial conjugation machinery

LC Beltran, V Cvirkaite-Krupovic, J Miller… - Nature …, 2023 - nature.com
Conjugation is a major mechanism of horizontal gene transfer promoting the spread of
antibiotic resistance among human pathogens. It involves establishing a junction between a …

A neglected risk of nanoplastics as revealed by the promoted transformation of plasmid‐borne ampicillin resistance gene by Escherichia coli

X Wang, H Li, Y Chen, X Meng… - Environmental …, 2022 - Wiley Online Library
Plastic pollution and antibiotic resistance are two emerging environmental and human
health crises today. Although it was revealed that microplastics can serve as vectors for the …

[HTML][HTML] The F-pilus biomechanical adaptability accelerates conjugative dissemination of antimicrobial resistance and biofilm formation

JB Patkowski, T Dahlberg, H Amin, DK Gahlot… - Nature …, 2023 - nature.com
Conjugation is used by bacteria to propagate antimicrobial resistance (AMR) in the
environment. Central to this process are widespread conjugative F-pili that establish the …

Competitive interference among rhizobia reduces benefits to hosts

A Rahman, M Manci, C Nadon, IA Perez, WF Farsamin… - Current Biology, 2023 - cell.com
The capacity of beneficial microbes to compete for host infection—and the ability of hosts to
discriminate among them—introduces evolutionary conflict that is predicted to destabilize …

Antifungal weapons of Lysobacter, a mighty biocontrol agent

L Lin, K Xu, D Shen, SH Chou… - Environmental …, 2021 - Wiley Online Library
Bacteria interact with fungi in a variety of ways to inhibit fungal growth, while the underlying
mechanisms remain only partially characterized. The plant‐beneficial Bacillus and …