[HTML][HTML] Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human …

AO Stucki, TS Barton-Maclaren, Y Bhuller… - Frontiers in …, 2022 - frontiersin.org
New approach methodologies (NAMs) are increasingly being used for regulatory decision
making by agencies worldwide because of their potential to reliably and efficiently produce …

Left-censored data and where to find them: Current implications in mycotoxin-related risk assessment, legislative and economic impacts

OA Mihalache, C Dall'Asta - Trends in Food Science & Technology, 2023 - Elsevier
Background One of the most challenging steps in chemical risk assessment is the dietary
exposure due to the high percentage of left-censored data (LCD). Mycotoxins are the group …

Alternatives to animal testing in toxicity testing: Current status and future perspectives in food safety assessments

N Reddy, B Lynch, J Gujral, K Karnik - Food and Chemical Toxicology, 2023 - Elsevier
The development of alternative methods to animal testing has gained great momentum
since Russel and Burch introduced the “3Rs” concept of Reduction, Refinement, and …

[HTML][HTML] Data analysis strategies for the characterization of chemical contaminant mixtures. Fish as a case study

C Simonnet-Laprade, S Bayen, B Le Bizec… - Environment …, 2021 - Elsevier
Thousands of chemicals are potentially contaminating the environment and food resources,
covering a wide spectrum of molecular structures, physico-chemical properties, sources …

Intake and risk assessment of nine priority food additives in Turkish adults

HM Bayram, A Ozturkcan - Journal of Food Composition and Analysis, 2022 - Elsevier
Exposure to excess food additives is a potential health risk for humans. This study aimed to
assess the dietary exposure to nine priority food additives in Turkey. The study took a …

Deterministic and Probabilistic Dietary Exposure Assessment to Deoxynivalenol in Spain and the Catalonia Region

JA Gallardo, S Marin, AJ Ramos, G Cano-Sancho… - Toxins, 2022 - mdpi.com
Deoxynivalenol (DON) remains one of the most concerning mycotoxins produced by the
Fusarium genus due to the wide occurrence in highly consumed cereal-based food and its …

In silico methods for environmental risk assessment: Principles, tiered approaches, applications, and future perspectives

MC Astuto, MR Di Nicola, JV Tarazona… - In Silico methods for …, 2022 - Springer
This chapter aims to introduce the reader to the basic principles of environmental risk
assessment of chemicals and highlights the usefulness of tiered approaches within weight of …

Quantitative determination of BPA, BPB, BPF and BPS levels in canned legumes from Italian market

ME Schiano, F Sodano, E Magli, A Corvino, F Fiorino… - Food Chemistry, 2023 - Elsevier
The levels of bisphenol A (BPA), bisphenol B (BPB), bisphenol F (BPF) and bisphenol S
(BPS) were monitored in twenty-three samples of canned legumes from popular brands …

TKPlate 1.0: An Open‐access platform for toxicokinetic and toxicodynamic modelling of chemicals to implement new approach methodologies in chemical risk …

JLCM Dorne, J Cortiñas‐Abrahantes… - EFSA …, 2023 - Wiley Online Library
This publication is linked to the following EFSA Supporting Publications articles:
http://onlinelibrary. wiley. com/doi/10.2903/sp. efsa. 2023. EN-8441/full, http://onlinelibrary …

The use of new approach methodologies for the environmental risk assessment of food and feed chemicals

MR Di Nicola, I Cattaneo, AV Nathanail… - Current opinion in …, 2023 - Elsevier
Abstract New Approach Methodologies (NAMs) provide tools for supporting both human and
environmental risk assessment (HRA and ERA). This short review provides recent insights …