Cells from virtually all organisms respond to a variety of stresses by the rapid synthesis of a
highly conserved set of polypeptides termed heat shock proteins (HSPs). The precise …

A well-regulated redox state is essential for normal physiological function and cellular
metabolism. In most eukaryotic cells, protein cysteine thiols are most sensitive to fluctuations …

How a cell responds to stress is a central problem in cardiovascular biology. Diverse
physiological stresses (eg, heat, hemodynamics, mutant proteins, and oxidative injury) …

Heat shock proteins (HSPs) such as HSP 60 (Hsp60), Hsp70, Hsp90, and gp96, have been
reported to play important roles in antigen presentation and cross-presentation, activation of …

In the eukaryotic cell an intrinsic mechanism is present providing the ability to defend itself
against external stressors from various sources. This defense mechanism probably evolved …

Extensive work in the last 10 years has suggested that heat shock proteins (HSPs) may be
potent activators of the innate immune system. It has been reported that Hsp60, Hsp70 …

Proliferation of mammalian cells can be controlled by low cultivation temperature. However,
depending on cell type and expression system, varying effects of a temperature shift on …

In addition to serving as molecular chaperones, heat shock proteins (HSPs) have been
implicated in autoimmune diseases, antigen presentation and tumor immunity. Extensive …

Commercially important oysters are often subject to mass mortality in the field. Rationalizing
that heat shock can induce tolerance to stresses other than heat, we are exploring the …

Changes in plasma levels of noradrenaline (NA), adrenaline (A), adrenocorticotropic
hormone (ACTH) and corticosterone (CORT), as well as in cytosol glucocorticoid receptor …