Alterations in the immune response that result in inflammation might play a role in the
pathology of dementias. In order to analyze changes of the peripheral immune system …

The recent developments in the study of clustered regularly interspaced short palindromic
repeats/associated protein 9 (CRISPR/Cas9) system have revolutionized the art of genome …

Two fundamental features characterize adaptive immunity: specific antigen recognition and
immunological memory development. Thus, B and T cells form the adaptive immune system …

Established widely metastatic tumor was cured in a transplanted mouse B cell lymphoma
model, by the combination of chemotherapy plus intratumoral injection of …

Evidence of tumor-resident mature B cell and antibody compartments and reports of
associations with favorable prognosis in malignant melanoma suggest that humoral …

Autophagy is a constitutive pathway that allows the lysosomal degradation of damaged
components. This conserved process is essential for metabolic plasticity and tissue …

Background Meningiomas often harbor an immune cell infiltrate that can include substantial
numbers of T and B cells. However, their phenotype and characteristics remain undefined …

CD1d-restricted invariant natural killer T (iNKT) cells play central roles in the activation and
regulation of innate and adaptive immunity. Cytokine-mediated and CD1d-dependent …

Simple Summary CAR-T cell therapy is a new approach to cancer treatment that is based on
manipulating a patient's own T cells such that they become able to seek and destroy cancer …

The ability to culture and expand B cells in vitro has become a useful tool for studying
human immunity. A limitation of current methods for human B cell culture is the capacity to …