Recent developments in isolating methods for exosomes

J Gao, A Li, J Hu, L Feng, L Liu, Z Shen - Frontiers in bioengineering …, 2023 - frontiersin.org
Exosomes are the smallest extracellular vesicles that can be released by practically all cell
types, and range in size from 30 nm to 150 nm. As the major marker of liquid biopsies …

Advances in extracellular vesicle nanotechnology for precision theranostics

Q Wu, S Fu, H Xiao, J Du, F Cheng, S Wan… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …

Machine learning-based label-free SERS profiling of exosomes for accurate fuzzy diagnosis of cancer and dynamic monitoring of drug therapeutic processes

X Diao, X Li, S Hou, H Li, G Qi, Y Jin - Analytical Chemistry, 2023 - ACS Publications
Exosomes are a class of extracellular vesicles secreted by cells, which can be used as
promising noninvasive biomarkers for the early diagnosis and treatment of diseases …

Selective In Situ Analysis of Mature microRNAs in Extracellular Vesicles Using a DNA Cage‐Based Thermophoretic Assay

S Zhao, S Zhang, H Hu, Y Cheng, K Zou… - Angewandte …, 2023 - Wiley Online Library
Mature microRNAs (miRNAs) in extracellular vesicles (EVs) are involved in different stages
of cancer progression, yet it remains challenging to precisely detect mature miRNAs in EVs …

Precise identification and profiling of surface proteins of ultra rare tumor specific extracellular vesicle with dynamic quantitative plasmonic imaging

C Zhai, J Long, J He, Y Zheng, B Wang, J Xu, Y Yang… - ACS …, 2023 - ACS Publications
Specific detection of tumor-derived EVs (tEVs) in plasma is complicated by nontumor EVs
and non-EV particles. To accurately identify tEVs and profile their surface protein expression …

Cascaded microfluidic circuits for pulsatile filtration of extracellular vesicles from whole blood for early cancer diagnosis

Z Li, C Liu, Y Cheng, Y Li, J Deng, L Bai, L Qin… - Science …, 2023 - science.org
Tumor-derived extracellular vesicles (EVs) hold the potential to substantially improve
noninvasive early diagnosis of cancer. However, analysis of nanosized EVs in blood …

Aptamer‐based extracellular vesicle isolation, analysis and therapeutics

L Zhu, W Tian, L Yuan, C Chi, Y Wang… - Interdisciplinary …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) play an important role in many physiological processes. Thus,
EV analysis has a great value for the understanding of mechanisms underlying disease …

Advanced technologies for molecular diagnosis of cancer: State of pre-clinical tumor-derived exosome liquid biopsies

L Li, L Zhang, KC Montgomery, L Jiang, CJ Lyon… - Materials Today Bio, 2023 - Elsevier
Exosomes are membrane-defined extracellular vesicles (EVs) approximately 40–160​ nm
in diameter that are found in all body fluids including blood, urine, and saliva. They act as …

Advanced microfluidic technologies for isolating extracellular vesicles

S Zhang, J Deng, J Li, F Tian, C Liu, L Fang… - TrAC Trends in Analytical …, 2022 - Elsevier
Extracellular vesicles (EVs) are lipid membrane-enclosed, cell-secreted nanovesicles that
have attracted significant attentions in recent years in view of their potential as non-invasive …

Printed divisional optical biochip for multiplex visualizable exosome analysis at point‐of‐care

X Yang, Z Zhang, Y Wu, H Wang, Y Yun… - Advanced …, 2024 - Wiley Online Library
Rapid detection of various exosomes is of great significance in early diagnosis and
postoperative monitoring of cancers. Here, a divisional optical biochip is reported for …