Hippo signaling pathway is an evolutionarily conserved network that regulates organ size
growth and tissue regeneration. Hippo signaling dysfunction results in uncontrolled cell …

Gastric cancer (GC) is an aggressive malignant disease which still lacks effective early
diagnosis markers and targeted therapies, representing the fourth-leading cause of cancer …

The circular RNAs (circRNAs) involved in competitive endogenous RNA (ceRNA)
mechanism are critical modulators affecting pathogenesis of thyroid carcinoma (TC). The …

Osteosarcoma (OS) is a cancer that is frequently found in children and adolescents and has
made little improvement in terms of prognosis in recent years. A recently discovered type of …

Objective Papillary thyroid carcinoma is treated in China mostly with surgery, including total
ablation, lobectomy, and lobe and isthmus resection. Therefore, whether thyroid status …

Abstract Background Phospholipase C Delta 3 (PLCD3) is a member of phospholipase C
(PLC) Protein and PLCD3 protein plays a prominent role in many cancers. However, little is …

Simple Summary Despite advances in primary and adjuvant treatments, approximately 50%
of colorectal cancer (CRC) patients still die from recurrence and metastatic disease. Thus …

Osteoarthritis is a heterogeneous disease with a complex etiology. However, there is no
effective treatment strategy at present. The purpose of this study was to explore the miRNA …

Metastasis is a fatal status for liver cancer, and the identification of an effective prediction
model and promising therapeutic target is essential. Given the known relationship between …

Gastric cancer (GC) is a heterogeneous disease whose development is accompanied by
alterations in a variety of pathogenic genes. The phospholipase C Delta 3 enzyme is a …