Type 1 diabetes
Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …
[PDF][PDF] Fecal microbiota transplantation in human metabolic diseases: from a murky past to a bright future?
NMJ Hanssen, WM de Vos, M Nieuwdorp - Cell metabolism, 2021 - cell.com
Fecal microbiota transplantation (FMT) is gaining considerable traction as a therapeutic
approach to influence the course of a plethora of chronic conditions, ranging from metabolic …
approach to influence the course of a plethora of chronic conditions, ranging from metabolic …
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes
CC Robertson, JRJ Inshaw, S Onengut-Gumuscu… - Nature …, 2021 - nature.com
We report the largest and most diverse genetic study of type 1 diabetes (T1D) to date
(61,427 participants), yielding 78 genome-wide-significant (P< 5× 10− 8) regions, including …
(61,427 participants), yielding 78 genome-wide-significant (P< 5× 10− 8) regions, including …
[HTML][HTML] Towards a better understanding of diabetes mellitus using organoid models
BS Beydag-Tasöz, S Yennek… - Nature Reviews …, 2023 - nature.com
Our understanding of diabetes mellitus has benefited from a combination of clinical
investigations and work in model organisms and cell lines. Organoid models for a wide …
investigations and work in model organisms and cell lines. Organoid models for a wide …
[PDF][PDF] Conformal coating of stem cell-derived islets for β cell replacement in type 1 diabetes
The scarcity of donors and need for immunosuppression limit pancreatic islet transplantation
to a few patients with labile type 1 diabetes. Transplantation of encapsulated stem cell …
to a few patients with labile type 1 diabetes. Transplantation of encapsulated stem cell …
Dual‐hormone artificial pancreas for management of type 1 diabetes: Recent progress and future directions
Over the last few years, technological advances have led to tremendous improvement in the
management of type 1 diabetes (T1D). Artificial pancreas systems have been shown to …
management of type 1 diabetes (T1D). Artificial pancreas systems have been shown to …
A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes
K Girdhar, Q Huang, IT Chow… - Proceedings of the …, 2022 - National Acad Sciences
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of
pancreatic β-cells. One of the earliest aspects of this process is the development of …
pancreatic β-cells. One of the earliest aspects of this process is the development of …
[HTML][HTML] Bone health in type 1 diabetes
Bone health in type 1 diabetes : Current Opinion in Endocrinology, Diabetes and Obesity Bone
health in type 1 diabetes : Current Opinion in Endocrinology, Diabetes and Obesity Log in or …
health in type 1 diabetes : Current Opinion in Endocrinology, Diabetes and Obesity Log in or …
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes
Abstract Type 1 diabetes (T1D) is characterized by pancreatic islet infiltration by autoreactive
immune cells and a nearly complete loss of β cells 1. Restoration of insulin-producing β cells …
immune cells and a nearly complete loss of β cells 1. Restoration of insulin-producing β cells …
Combination of vitamin D and dipeptidyl peptidase-4 inhibitors (VIDPP-4i) as an immunomodulation therapy for autoimmune diabetes
Abstract Type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA) represent
the most common types of autoimmune diabetes and are characterized by different age of …
the most common types of autoimmune diabetes and are characterized by different age of …