[HTML][HTML] Cannabidiol (CBD) as a promising anti-cancer drug

ES Seltzer, AK Watters, D MacKenzie, LM Granat… - Cancers, 2020 - mdpi.com
Recently, cannabinoids, such as cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (THC),
have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a …

The diverse mechanisms and anticancer potential of naphthoquinones

CE Pereyra, RF Dantas, SB Ferreira, LP Gomes… - Cancer Cell …, 2019 - Springer
Cancer is one of the leading causes of death around the world and although the different
clinical approaches have helped to increase survival rates, incidence is still high and so its …

Antioxidant role of kaempferol in prevention of hepatocellular carcinoma

N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …

Apoptosis, autophagy and atherosclerosis: relationships and the role of Hsp27

R Shan, N Liu, Y Yan, B Liu - Pharmacological research, 2021 - Elsevier
Atherosclerosis is a multifactorial chronic inflammatory disease of the arterial wall, and an
important pathological basis of coronary heart disease. Endothelial cells, vascular smooth …

The emerging role of paraptosis in tumor cell biology: Perspectives for cancer prevention and therapy with natural compounds

F Fontana, M Raimondi, M Marzagalli… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Standard anti-cancer therapies promote tumor growth suppression mainly via induction of
apoptosis. However, in most cases cancer cells acquire the ability to escape apoptotic cell …

Interactions of zinc oxide nanostructures with mammalian cells: cytotoxicity and photocatalytic toxicity

C Liao, Y Jin, Y Li, SC Tjong - International journal of molecular sciences, 2020 - mdpi.com
This article presents a state-of-the-art review and analysis of literature studies on the
morphological structure, fabrication, cytotoxicity, and photocatalytic toxicity of zinc oxide …

Paraptosis: a unique cell death mode for targeting cancer

S Hanson, A Dharan, J PV, S Pal, BG Nair… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death (PCD) is the universal process that maintains cellular homeostasis
and regulates all living systems' development, health and disease. Out of all, apoptosis is …

Flaxseed lignans as important dietary polyphenols for cancer prevention and treatment: Chemistry, pharmacokinetics, and molecular targets

SF De Silva, J Alcorn - Pharmaceuticals, 2019 - mdpi.com
Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …

New visions on natural products and cancer therapy: autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

Apigenin induces autophagy and cell death by targeting EZH2 under hypoxia conditions in gastric cancer cells

TW Kim, HG Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
Hypoxia is a major obstacle to gastric cancer (GC) therapy and leads to chemoresistance as
GC cells are frequently exposed to the hypoxia environment. Apigenin, a flavonoid found in …