Ion‐Engineered Microcryogels via Osteogenesis‐Angiogenesis Coupling and Inflammation Reversing Augment Vascularized Bone Regeneration
Y Wang, X Wang, Y Pang, X Li, C Gao… - Advanced Functional …, 2024 - Wiley Online Library
Native bone inherently requires a balanced ionic microenvironment to maintain bone
homeostasis. Hence, scaffolds designed for the sustained release of therapeutic ions into …
homeostasis. Hence, scaffolds designed for the sustained release of therapeutic ions into …
Mg-Cross-Linked Alginate Hydrogel Induces BMSC/Macrophage Crosstalk to Enhance Bone Tissue Regeneration via Dual Promotion of the Ligand–Receptor Pairing …
L Gu, R Huang, N Ni, R Zhou, Y Su, P Gu… - … Applied Materials & …, 2024 - ACS Publications
Macrophages play a pivotal role in the crosstalk between the immune and skeletal systems,
while Mg-based biomaterials demonstrate immunomodulatory capabilities in this procedure …
while Mg-based biomaterials demonstrate immunomodulatory capabilities in this procedure …
A hydrogel containing Mg2+ with improved osteogenesis, enhanced endochondral ossification, and modulated inflammation for bone-repair applications
J Liao, J Zhang, J Li, Y Zeng, Y Dai, T Xiao… - Chemical Engineering …, 2024 - Elsevier
In this study, an injectable, porous, and Mg 2+-loaded hydrogel with the ability to scavenge
local reactive oxygen species was developed for bone-repair applications. Alendronate …
local reactive oxygen species was developed for bone-repair applications. Alendronate …
[HTML][HTML] Diatomite-incorporated hierarchical scaffolds for osteochondral regeneration
C Deng, C Qin, Z Li, L Lu, Y Tong, J Yuan, F Yin… - Bioactive Materials, 2024 - Elsevier
Osteochondral regeneration involves the highly challenging and complex reconstruction of
cartilage and subchondral bone. Silicon (Si) ions play a crucial role in bone development …
cartilage and subchondral bone. Silicon (Si) ions play a crucial role in bone development …
[HTML][HTML] Regulation of metabolic microenvironment with a nanocomposite hydrogel for improved bone fracture healing
K Zha, M Tan, Y Hu, W Hu, S Zhang, Y Zhao, Z Lin… - Bioactive Materials, 2024 - Elsevier
Bone nonunion poses an urgent clinical challenge that needs to be addressed. Recent
studies have revealed that the metabolic microenvironment plays a vital role in fracture …
studies have revealed that the metabolic microenvironment plays a vital role in fracture …
[HTML][HTML] Selective ion doping core-shell bioceramic fiber-derived granules readily tuning biodegradation and initiating osteoporotic bone defect repair
J Shen, Y Li, J Li, M Shen, Y Xu, Y Zhang, X Yang… - Materials & Design, 2024 - Elsevier
Osteoporotic bone defect repair is one of the challenges in orthopedics because there are
no preferable biomaterials to readily initiate new bone regeneration in critical-size …
no preferable biomaterials to readily initiate new bone regeneration in critical-size …
An Injectable Magnesium‐Based Cement Stimulated with NIR for Drug‐Controlled Release and Osteogenic Potential
Y Zhao, Y Li, B Wang, J Yao, Y Fan… - Advanced …, 2024 - Wiley Online Library
Magnesium phosphate bone cement (MPC) has gained widespread usage in orthopedic
implantation due to its fast‐setting and high initial strength benefits. However, the …
implantation due to its fast‐setting and high initial strength benefits. However, the …
3d Bioprinting of a Calcium Phosphate Scaffold Containing Degradable Microfibers Encapsulating Hpdlscs with Two-Staged Release of Nell-1 for Bone-Vascular …
M Zhu, K Yu, HHK Xu, MD Weir, A Schneider… - Available at SSRN … - papers.ssrn.com
Regeneration of large bone defects remains a major clinical challenge due to the lack of
vasculature and innervation. Few studies have focused on the regeneration of all three …
vasculature and innervation. Few studies have focused on the regeneration of all three …