Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …

The association of an individual's genetic makeup with their response to drugs is referred to
as pharmacogenomics. By understanding the relationship between genetic variants and …

There has been a systematic and largely unconscious neglect of gender in palliative care
research, practice and policy. This is despite significant, although previously uncollated …

Pain is a major source of global suffering, with women bearing the greatest burden.
Alongside biology, psychological and social factors, including gender, help explain these …

Purpose Transcutaneous electrical nerve stimulation (TENS) is a treatment option for cancer
pain, but the evidence is inconclusive. We aimed to evaluate the efficacy and safety of …

The major challenges that delay the implementation of pharmacogenomics based clinical
practice in the developing countries, primarily the low-and middle-income countries need to …

Tapentadol (TAP) and oxycodone/naloxone (OXN) potentially offer an improved opioid
tolerability. However, real-world studies in chronic non-cancer pain (CNCP) remain scarce …

Introduction: Opioid deprescription is the process of supervised tapering and safe
withdrawal when a potentially inappropriate use is detected. This represents a challenge in …

Despite the large body of research on sex differences in pain, there is a lack of translation to
real-world pain management. Our aim was to analyse the sex differences in the analgesic …

(1) Background: It is essential to focus attention on sex-specific factors which are clinically
relevant in pain management, especially with regards to opioid use disorder (OUD) risk. The …