Tetrahedral framework nucleic acids reestablish immune tolerance and restore saliva secretion in a sjogren's syndrome mouse model
S Gao, Y Wang, Y Li, D Xiao, Y Lin… - ACS Applied Materials …, 2021 - ACS Publications
As one of the most frequent autoimmune diseases, Sjogren's syndrome (SS) is
characterized by overactive lymphocytic infiltration in the exocrine glands, with ensuing dry …
characterized by overactive lymphocytic infiltration in the exocrine glands, with ensuing dry …
Patient-derived xenografts or organoids in the discovery of traditional and self-assembled drug for tumor immunotherapy
W Zhang, X Zheng - Frontiers in Oncology, 2023 - frontiersin.org
In addition to the rapid development of immune checkpoint inhibitors, there has also been a
surge in the development of self-assembly immunotherapy drugs. Based on the immune …
surge in the development of self-assembly immunotherapy drugs. Based on the immune …
Next-Generation Vaccine Development with Nanomaterials: Recent Advances, Possibilities, and Challenges
S Shetty, PC Alvarado, D Pettie… - Annual Review of …, 2024 - annualreviews.org
Nanomaterials are becoming important tools for vaccine development owing to their tunable
and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate …
and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate …
Engineering living cells with cucurbit [7] uril-based supramolecular polymer chemistry: from cell surface engineering to manipulation of subcellular organelles
F Huang, J Liu, Y Liu - Chemical Science, 2022 - pubs.rsc.org
Supramolecular polymer chemistry, which closely integrates noncovalent interactions with
polymeric structures, is a promising toolbox for living cell engineering. Here, we report our …
polymeric structures, is a promising toolbox for living cell engineering. Here, we report our …
Triply enhanced immunotherapy via dual glycan reforming integrated with perforation
Y Yang, Y Wang, Z Chao, Y Yang, Y Fang… - Advanced …, 2024 - Wiley Online Library
The enhancement of immunotherapy is an emerging direction to develop highly effective
and practical cancer therapeutic methods. Here a triply enhanced immunotherapy drug …
and practical cancer therapeutic methods. Here a triply enhanced immunotherapy drug …
Macrophage‐mediated delivery of hypoxia‐activated prodrug nanoparticles
Hypoxia‐activated prodrugs (HAPs) have tremendous clinical potential due to their selective
toxicity toward poorly oxygenated tissues, which is a hallmark of solid tumors. Despite their …
toxicity toward poorly oxygenated tissues, which is a hallmark of solid tumors. Despite their …
Photoresponsive polypeptide-glycosylated dendron amphiphiles: UV-triggered polymersomes, OVA release, and in vitro enhanced uptake and immune response
Y Song, Y Chen, P Li, CM Dong - Biomacromolecules, 2020 - ACS Publications
Efficient therapeuic proteins' delivery into mammalian cells and subcellular transport (eg,
fast escape from endolysosomes into cytoplasm) are two key biological barriers that need to …
fast escape from endolysosomes into cytoplasm) are two key biological barriers that need to …
Nanotechnology-based approaches to promote lymph node targeted delivery of cancer vaccines
R He, J Zang, Y Zhao, H Dong, Y Li - ACS Biomaterials Science & …, 2022 - ACS Publications
Vaccines are a promising immunotherapy that awakens the human immune system to inhibit
and eliminate cancer with fewer side effects compared with traditional radiotherapy and …
and eliminate cancer with fewer side effects compared with traditional radiotherapy and …
Uncoupling therapeutic efficacy from immune-related adverse events in immune checkpoint blockade
W Hu, G Wang, Y Wang, MJ Riese, M You - IScience, 2020 - cell.com
Immunotherapy with monoclonal antibodies targeting immune checkpoint molecules,
including programmed death-1 (PD-1), PD ligand-1 (PD-L1), and cytotoxic T-lymphocyte …
including programmed death-1 (PD-1), PD ligand-1 (PD-L1), and cytotoxic T-lymphocyte …
Engineered multifunctional nano‐and biological materials for cancer immunotherapy
A Brouillard, N Deshpande… - Advanced Healthcare …, 2021 - Wiley Online Library
Cancer immunotherapy is set to emerge as the future of cancer therapy. However, recent
immunotherapy trials in different cancers have yielded sub‐optimal results, with durable …
immunotherapy trials in different cancers have yielded sub‐optimal results, with durable …