Autosomal-dominant polycystic kidney disease (ADPKD) affects up to 12 million individuals
and is the fourth most common cause for renal replacement therapy worldwide. There have …

Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal,
monogenic disorder. It is associated with large interfamilial and intrafamilial variability, which …

A second gene for autosomal dominant polycystic kidney disease was identified by
positional cloning. Nonsense mutations in this gene (PKD2) segregated with the disease in …

Shortly after being elbowed in the flank during a basketball game, a 35-year-old healthy
man has severe, colicky abdominal pain followed by gross hematuria. A renal ultrasound …

Autosomal dominant polycystic kidney disease (PKD) is a hereditary condition characterized
by the progressive enlargement of innumerable renal cysts that contribute to life-altering …

The rate of disease progression in autosomal-dominant polycystic kidney disease (ADPKD)
has high intrafamilial variability, suggesting that environmental factors may play a role. We …

Autosomal dominant polycystic kidney disease (ADPKD) is generally a late-onset
multisystem disorder characterized by bilateral kidney cysts, liver cysts, and an increased …

Pain management in polycystic kidney disease. Pain is a common complaint in patients with
autosomal-dominant polycystic kidney disease, and a systematic approach is needed to …

Magnetic materials in tissue, such as iron, calcium, or collagen, can be studied using
quantitative susceptibility mapping (QSM). To date, QSM has been overwhelmingly applied …

Ketogenic dietary interventions (KDIs) are beneficial in animal models of autosomal-
dominant polycystic kidney disease (ADPKD). KETO-ADPKD, an exploratory, randomized …