Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation

B Long, BM Carius, S Chavez, SY Liang… - The American journal of …, 2022 - Elsevier
Introduction Coronavirus disease of 2019 (COVID-19) has resulted in millions of cases
worldwide. As the pandemic has progressed, the understanding of this disease has evolved …

An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

[HTML][HTML] The inter-relationship between delirium and dementia: the importance of delirium prevention

TG Fong, SK Inouye - Nature Reviews Neurology, 2022 - nature.com
Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …

[HTML][HTML] Delirium in critical illness: clinical manifestations, outcomes, and management

JL Stollings, K Kotfis, G Chanques, BT Pun… - Intensive care …, 2021 - Springer
Delirium is the most common manifestation of brain dysfunction in critically ill patients. In the
intensive care unit (ICU), duration of delirium is independently predictive of excess death …

[HTML][HTML] Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations

M Parotto, M Gyöngyösi, K Howe, SN Myatra… - The Lancet …, 2023 - thelancet.com
Individuals with SARS-CoV-2 infection can develop symptoms that persist well beyond the
acute phase of COVID-19 or emerge after the acute phase, lasting for weeks or months after …

[HTML][HTML] Cerebral dysfunctions caused by sepsis during ageing

T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …

[HTML][HTML] CSF biomarkers in COVID-19 associated encephalopathy and encephalitis predict long-term outcome

M Guasp, G Muñoz-Sánchez… - Frontiers in …, 2022 - frontiersin.org
Patients with coronavirus disease 2019 (COVID-19) frequently develop acute
encephalopathy and encephalitis, but whether these complications are the result from viral …

[HTML][HTML] Prevalence of post-intensive care syndrome in mechanically ventilated patients with COVID-19

K Nanwani-Nanwani, L López-Pérez… - Scientific reports, 2022 - nature.com
Abstract Coronavirus disease 19 (COVID-19) patients usually require long periods of
mechanical ventilation and sedation, which added to steroid therapy, favours a …

Coronavirus disease 2019 as cause of viral sepsis: a systematic review and meta-analysis

E Karakike, EJ Giamarellos-Bourboulis… - Critical care …, 2021 - journals.lww.com
Objective: Coronavirus disease 2019 is a heterogeneous disease most frequently causing
respiratory tract infection, which can induce respiratory failure and multiple organ …

[HTML][HTML] Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis

LD Burry, W Cheng, DR Williamson, NK Adhikari… - Intensive care …, 2021 - Springer
Purpose To compare the effects of prevention interventions on delirium occurrence in
critically ill adults. Methods MEDLINE, Embase, PsychINFO, CINAHL, Web of Science …