Inflammatory factors, genetic variants, and predisposition for preterm birth

J Couceiro, I Matos, JJ Mendes, PV Baptista… - Clinical …, 2021 - Wiley Online Library
Preterm birth is a major clinical and public health challenge, with a prevalence of 11%
worldwide. It is the leading cause of death in children younger than 5 years old and …

A functional genomics predictive network model identifies regulators of inflammatory bowel disease

LA Peters, J Perrigoue, A Mortha, A Iuga, W Song… - Nature …, 2017 - nature.com
A major challenge in inflammatory bowel disease (IBD) is the integration of diverse IBD data
sets to construct predictive models of IBD. We present a predictive model of the immune …

The association between IL-1 family gene polymorphisms and colorectal cancer: A meta-analysis

L Liu, Z Zhai, D Wang, Y Ding, X Chen, Q Wang, Z Shu… - Gene, 2021 - Elsevier
Background Colorectal cancer (CRC) is a major public health problem given its high
incidence and mortality. This study focuses on examining the associations between IL-1α, IL …

Differential intestinal mucosa transcriptomic biomarkers for Crohn's disease and ulcerative colitis

M Dobre, E Milanesi, TE Mănuc… - Journal of …, 2018 - Wiley Online Library
Genetic research has shaped the inflammatory bowel disease (IBD) landscape identifying
nearly two hundred risk loci. Nonetheless, the identified variants rendered only a partial …

Identification of differential intestinal mucosa transcriptomic biomarkers for ulcerative colitis by bioinformatics analysis

F Cheng, Q Li, J Wang, F Zeng, K Wang… - Disease …, 2020 - Wiley Online Library
Background. Ulcerative colitis (UC) is a complicated disease caused by the interaction
between genetic and environmental factors that affect mucosal homeostasis and triggers …

[HTML][HTML] Interleukin (IL)-1 gene cluster in inflammatory bowel disease: is IL-1RA implicated in the disease onset and outcome?

M Muro, A Mrowiec - Digestive Diseases and Sciences, 2015 - Springer
The two major types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), whose
etiology involves immunological and environmental factors. CD and UC share some …

Discs large homolog 5 (DLG5) gene polymorphism and Crohn's disease: a meta-analysis of the published studies

A Shafieyoun, S Moraveji, M Bashashati… - Acta Medica …, 2016 - acta.tums.ac.ir
The real pathophysiology of Crohn's disease is unknown. The higher prevalence of Crohn's
disease in Caucasian and Jewish ethnicities, as well as its familial aggregation and higher …

Interleukin-1 single nucleotide polymorphisms as risk factors for susceptibility of inflammatory bowel disease: an Iraqi Arab population-based study

AH Ad'hiah, EB Hessan, BA Shahab - Alexandria Journal of …, 2019 - Taylor & Francis
Objectives: It is aimed to determine the association between four single-nucleotide
polymorphisms (SNPs) of IL1 genes (rs1800587: IL1A− 889 C/T, rs16944: IL1B− 511 T/C …

ÜLSERATİF KOLİT MODELİNDE FARKLI DOZLARDA UYGULANAN Cannabis sativa TOHUMU YAĞININ OLASI ETKİLERİNİN ARAŞTIRILMASI

İ Kavak - 2024 - adudspace.adu.edu.tr
Ülseratif Kolit Modelinde Farklı Dozlarda Uygulanan Cannabis sativa Tohumu Yağının Olası
Etkilerinin Araştırılması Kavak İ. Aydın Adnan Menderes Üniversitesi, Sağlık Bilimleri …

Crohn hastalığında vitamin d reseptörü ve ınterlökin gen ailesi tek nükleotit polimorfizmlerinin belirlenmesi

S Aksu - 2019 - openaccess.iku.edu.tr
Crohn hastalığı, öncelikle sindirim sistemini etkileyen, karmaşık, uzun süreli, kronik bir
bağırsak hastalığıdır. Aşırı iltihaplanmaya neden olan anormal bağışıklık yanıtları içerir …