The management of heart failure has changed significantly over the last 30 years, leading to
improvements in the quality of life and outcomes, at least for patients with a substantially …

Introduction Torsemide is a loop diuretic that inhibits the Na+/K+/2Cl− cotransporter type 2 in
the thick ascending loop of Henle, leading to increased excretion of urinary sodium and …

Background There have been ongoing efforts to understand when and how data from
observational studies can be applied to clinical and regulatory decision making. The …

The pharmacologic management of HFpEF is an evolving field. Symptomatic management
with diuretics and optimization of comorbidities remain important components of therapy …

Background Torasemide is a potent loop diuretic with potential to treat congestive heart
failure (CHF) in dogs. Objective Evaluate the efficacy and safety of torasemide compared to …

This review paper presents a review of the evolution of this disease throughout the
centuries, describes and summarizes the pathophysiologic mechanisms, briefly discusses …

To the Editor, Heart failure (HF) is a leading cause of morbidity and mortality globally. 1 Loop
diuretics, such as torsemide and furosemide, are routinely used for managing fluid overload …

Decompensated heart failure accounts for approximately 1 million hospitalizations in the
United States annually, and this number is expected to increase significantly in the near …

Background and objective Despite potential advantages of torsemide over furosemide,<
10% of the patients with heart failure (HF) are on torsemide in clinical practice. Prior studies …

A simple and accurate method to determinate furosemide (FUR) based on converting the
secondary amine to primary amine with acidic hydrolysis then azotization by nitrous acid …