Parallel actin bundles are present in a diverse array of structures, where they are critical
determinants of cellular shape and physiology. In the past 18 months, new findings have …

Acute renal failure (ARF) necessitating renal replacement therapy is a common problem
associated with high morbidity and mortality in the critically ill. Hypotension, followed by …

Rho GTPases control a variety of cellular processes, including actin polymerization, integrin
complex formation, cell adhesion, gene transcription, cell cycle progression, and cell …

The thoroughly updated Eighth Edition of this classic three-volume work provides the most
comprehensive, current, and authoritative information on diseases of the kidney and urinary …

The small G proteins of the Rho family are involved in reorganization of the actin
cytoskeleton, cell migration and in the regulation of gene transcription. Hypoxia-induced …

Monitoring changes in gene expression in renal ischemia-reperfusion in the rat Background
Although acute renal failure (ARF) is a relatively common disorder with major morbidity and …

There is growing evidence that microRNAs are implicated in pulmonary arterial
hypertension (PAH), but underlying mechanisms remain elusive. Here, we identified that …

The NPC is the portal for the exchange of proteins, mRNA, and ions between nucleus and
cytoplasm. Many small molecules (< 10kDa) permeate the nucleus by simple diffusion …

The signal transduction pathways involved in neuronal death are not well understood.
Neuroglobin (Ngb), a recently discovered vertebrate globin expressed predominantly in the …

DISCUSSION DR. BRUCE A. MOLITORIS (Director, Nephrology Division, Professor of
Medicine, and Director, Indiana Center for Biological Microscopy, Indiana University School …