Influence of organic solvents on secondary brain damage after experimental traumatic brain injury
J Walter, J Schwarting, N Plesnila… - Neurotrauma …, 2020 - liebertpub.com
Many compounds tested for a possible neuroprotective effect after traumatic brain injury
(TBI) are not readily soluble and therefore organic solvents need to be used as a vehicle. It …
(TBI) are not readily soluble and therefore organic solvents need to be used as a vehicle. It …
Vehicles for lipophilic drugs: implications for experimental design, neuroprotection, and drug discovery
J Rivers-Auty, JC Ashton - Current neurovascular research, 2013 - ingentaconnect.com
The delivery of some classes of drugs is challenging. Solubility, absorption, distribution, and
duration of action may all be altered by combination with vehicle molecules. It has already …
duration of action may all be altered by combination with vehicle molecules. It has already …
Nervous System Disorders
Bacterial meningoencephalomyelitis (MEM) is a possible complication of neonatal sepsis in
up to 8–10% of septic foals and has a high mortality rate. This chapter reviews MEM in …
up to 8–10% of septic foals and has a high mortality rate. This chapter reviews MEM in …
Special issues in brain plasticity, repair and rehabilitation: 20 years of a publishing strategy
BA Sabel, S Matzke, S Prilloff - Restorative Neurology and …, 2010 - content.iospress.com
Abstract The journal Restorative Neurology and Neuroscience (RNN) is focused on the
emerging field of brain plasticity, repair and rehabilitation, including original and review …
emerging field of brain plasticity, repair and rehabilitation, including original and review …
[HTML][HTML] Diazoxide blocks or reduces microgliosis when applied prior or subsequent to motor neuron injury in mice
Abstract Diazoxide (DZX), an anti-hypertonic and anti-hypoglycemic drug, was shown to
have anti-inflammatory effects in several injured cell types outside the central nervous …
have anti-inflammatory effects in several injured cell types outside the central nervous …
[HTML][HTML] 不同浓度的二甲基亚砜对斑马鱼胚胎及其多巴胺能神经元发育的影响
甘津凡, 吴永梅, 李淑蓉, 苏炳银 - 2019 - aammt.tmmu.edu.cn
目的研究不同浓度的二甲基亚砜(dimethylsulfoxide, DMSO) 对斑马鱼胚胎, 多巴胺能(
dopaminergic, DA) 神经元发育的影响. 方法收集同亲代Tg (Vmat2: GFP) 斑马鱼产下的胚胎 …
dopaminergic, DA) 神经元发育的影响. 方法收集同亲代Tg (Vmat2: GFP) 斑马鱼产下的胚胎 …
Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice
Misoprostol is a synthetic analogue of prostaglandin E1 that is administered to women at
high doses to induce uterine contractions for early pregnancy termination and at low doses …
high doses to induce uterine contractions for early pregnancy termination and at low doses …
Failed neuroprotection of combined inhibition of L-type and ASIC1a calcium channels with nimodipine and amiloride
J Ort, B Kremer, L Grüßer… - International journal of …, 2020 - mdpi.com
Effective pharmacological neuroprotection is one of the most desired aims in modern
medicine. We postulated that a combination of two clinically used drugs—nimodipine (L …
medicine. We postulated that a combination of two clinically used drugs—nimodipine (L …
Interactions of sulforaphane and dimethyl sulfoxide with methyl methanesulfonate, urethane, 4-nitroquinoline-1-oxide and hydrogen peroxide in the Drosophila …
IE Dueñas-García, LF Santos-Cruz… - Food and chemical …, 2012 - Elsevier
Sulforaphane (SF) is an isothiocyanate present in Brassicaceae, vegetables that induce the
detoxification of electrophiles and reactive oxygen species. SF has been correlated with …
detoxification of electrophiles and reactive oxygen species. SF has been correlated with …
The Effects of Cathepsin B Inhibition in the Face of Diffuse Traumatic Brain Injury and Secondary Intracranial Pressure Elevation
M Hernandez, S Regan, R Ansari, A Logan-Wesley… - 2024 - preprints.org
Traumatic brain injury (TBI) affects millions of people each year. Previous studies using the
central fluid percussion injury (CFPI) model in adult male rats indicated that elevated …
central fluid percussion injury (CFPI) model in adult male rats indicated that elevated …